Meta‐analysis on the association between the frequency of tooth brushing and diabetes mellitus risk

Fu, Wenning; Lv, Chuanzhu; Zou, Li; Zeng, Xian‐Tao; Wang, Chao; Yan, Shijiao; Gan, Yong; Fan, Chenyu; Lu, Zuxun; Cao, Shiyi

doi:10.1002/dmrr.3141

Cited by 13 publications

(17 citation statements)

References 38 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Our overall findings are in line with other systematic reviews and meta-analyses that demonstrated an association between oral health or hygiene and metabolic conditions [9,37]. Poor oral hygiene not only leads to dental infections, such as periodontitis, but it may also affect systemic health [55].…”

Section: Discussionsupporting

confidence: 91%

“…The OR was used as the common measure for the association between oral hygiene and MetS. The reported RR was considered approximately as OR [37]. The data utilized in the meta-analysis were the estimates and the corresponding 95% CI from the most adjusted model in the studies.…”

Section: Statistical Analysesmentioning

confidence: 99%

“…Heterogeneity was assessed using the I 2 statistic, with the value of ≥50% representing substantial heterogeneity [37,39]. Potential sources of heterogeneity were assessed using prespecified subgroup analyses by study design and country.…”

Section: Statistical Analysesmentioning

confidence: 99%

See 2 more Smart Citations

Association between Oral Hygiene and Metabolic Syndrome: A Systematic Review and Meta-Analysis

Santoso

Ketti

Bramantoro

et al. 2021

JCM

View full text Add to dashboard Cite

Emerging evidence has linked poor oral hygiene to metabolic syndrome (MetS), but previously, no summary of evidence has been conducted on the topic. This systematic review and meta-analysis aims to evaluate the associations of oral hygiene status and care with MetS. A systematic search of the PubMed and Web of Science databases from inception to March 17, 2021, and examination of reference lists was conducted to identify eligible observational studies. A random-effects model was applied to pool the effects of oral hygiene status and care on MetS. Thirteen studies met the inclusion criteria and had sufficient methodological quality. Good oral hygiene status (OR = 0.30 (0.13–0.66); I2 = 91%), frequent tooth brushing (OR = 0.68 (0.58–0.80); I2 = 89%), and frequent interdental cleaning (OR = 0.89 (0.81–0.99); I2 = 27%) were associated with a lower risk of MetS. Only one study examined the association between dental visits and MetS (OR = 1.10 (0.77–1.55)). Our findings suggested that there might be inverse associations of oral hygiene status, tooth-brushing frequency, and interdental cleaning with MetS. However, substantial heterogeneity for tooth-brushing frequency and inconsistent results for oral hygiene status in subgroup analyses were observed. There was insufficient evidence for the association between dental visits and MetS. Further longitudinal studies are needed to investigate these associations.

show abstract

Section: Discussionsupporting

confidence: 91%

Section: Statistical Analysesmentioning

confidence: 99%

See 1 more Smart Citation

Association between Oral Hygiene and Metabolic Syndrome: A Systematic Review and Meta-Analysis

Santoso

Ketti

Bramantoro

et al. 2021

JCM

View full text Add to dashboard Cite

show abstract

“…A meta-analysis of observational studies published in 2019 examined the relationship between frequency of tooth brushing and diabetes mellitus and concluded that people who brush their teeth more frequently are less likely to develop diabetes mellitus (Fu et al 2019). In a cohort study conducted in Japan, less frequency of tooth brushing was significantly associated with diabetes mellitus in men and dyslipidemia in women, while there was no significant association between frequency of tooth brushing and hypertension (Kuwabara et al 2017).…”

Section: Brushing Teeth After Mealsmentioning

confidence: 99%

Who Are Free from Hypertension, Dyslipidemia, and Diabetes Mellitus in the Middle-Aged and Elderly Population of Japan?

Sekizawa

Konishi

2021

Economics, Law, and Institutions in Asia Pacific

View full text Add to dashboard Cite

In the present study, we explored who are more (less) likely to be diagnosed with mild lifestyle-related diseases (MLDs) defined as hypertension, dyslipidemia, and diabetes mellitus as a whole among middle-aged and elderly persons. Data from 11 years of the Longitudinal Survey of Middle-Aged and Elderly Persons by the Japanese Ministry of Health, Labour and Welfare were used for the analyses. A complementary log-log model was chosen for the analyses. For men, those who drink alcohol were more likely to be diagnosed with MLDs. Former smokers were more likely to be diagnosed with MLDs than current smokers. Men who perform light exercise four days or more per week or those who perform vigorous exercise one to three days per week were less likely to be diagnosed with MLDs than those who did not exercise or exercised about one day per month. Men who take care of eating amounts were more likely to be diagnosed with MLDs. Men who brush teeth after meals were less likely to be diagnosed with MLDs. For women, those who drink alcohol were less likely to be diagnosed with MLDs. Former smokers were more likely to be diagnosed with MLDs than current smokers. Women who perform moderate exercise four days or more per week were more likely to be diagnosed with MLDs than those who did not exercise or exercised about one day per month. Women who take care of their eating amount or take vitamin/mineral supplements were more likely to be diagnosed with MLDs. Women who eat a variety of foods or maintain appropriate body weight levels were less likely to be diagnosed with MLDs. Some of these results are inconsistent with previous studies, are contrary to current understanding, or are not well known. Hence, further studies with a greater focus on causal relationships are required.

show abstract

“…Past studies have shown that increasing the frequency of toothbrushing lowers the risk of cardiovascular events [22] and T2DM [23] and may improve the condition of rheumatoid arthritis [24]. The anti-inflammatory effect of the removal of bacterial plaque is assumed to be the reason for these systemic positive effects.…”

Section: Introductionmentioning

confidence: 99%

Association between the Frequency of Daily Toothbrushing and Development of Nonalcoholic Fatty Liver Disease

Yamamoto

Ikeya

Okuyama

et al. 2021

Dig Dis

View full text Add to dashboard Cite

Background & Aims: This study aimed to evaluate the association between the frequency of daily tooth brushing and the development of nonalcoholic fatty liver disease (NAFLD). Methods: A retrospective longitudinal study was conducted from 2005 to 2012 at the Center for Preventive Medicine at St. Luke's International Hospital, Japan. Data on all participants who underwent a health checkup during the study period were collected. NAFLD was diagnosed by abdominal ultrasonography, and all participants who were diagnosed with NALFD at the time of their initial visit, consumed alcohol in any amount, or had received only one health checkup were excluded. The questionnaire for the frequency of daily tooth brushing was conducted as part of health checkups. The primary outcome was the risk of developing NAFLD according to the frequency of daily tooth brushing (1-2 times a day, or 3 times a day) compared to those who brush teeth once or less than once a day. Results: Data were collected from 25,804 people. A total of 3,289 (12.7%) participants developed NAFLD. The mean age was 45.2 years, and 6,901 (26.7%) of the participants were male. The risk of developing NAFLD significantly decreased with increased frequency of daily tooth brushing. Adjusted odds ratios (ORs) are as follows: Brushing teeth 1-2 times a day (OR: 0.85, 95% CI: 0.77-0.95), and 3 times a day (OR: 0.74, 95% CI: 0.67-0.82). Conclusions: Frequent tooth brushing was shown to significantly reduce the risk of developing NAFLD.

show abstract

Meta‐analysis on the association between the frequency of tooth brushing and diabetes mellitus risk

Cited by 13 publications

References 38 publications

Association between Oral Hygiene and Metabolic Syndrome: A Systematic Review and Meta-Analysis

Association between Oral Hygiene and Metabolic Syndrome: A Systematic Review and Meta-Analysis

Who Are Free from Hypertension, Dyslipidemia, and Diabetes Mellitus in the Middle-Aged and Elderly Population of Japan?

Association between the Frequency of Daily Toothbrushing and Development of Nonalcoholic Fatty Liver Disease

Contact Info

Product

Resources

About