Mercury pigmentation. An electron microscopic study

Burge, K. M.

doi:10.1001/archderm.102.1.51

Cited by 13 publications

(5 citation statements)

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“…It appears probable that our patients were exposed to the fumes of these metals while involved in the refining of the crude silver-containing ores. The ultrastructural localization of these additional elements was the same as silver and it is of interest that a similar localization has been described in a case of mercury pigmentation (Burge & Winkelmann, 1970). An ultrastructural and analytical electron microscopic study of a case of mercury pigmentation due to industrial exposure (Kennedy et al, 1977) found electron-dense 400-900 nm aggregates of 12 nm particles in dermal macrophages and free in the dermis.…”

Section: Electron Microscopymentioning

confidence: 56%

Occupational argyria; light and electron microscopic studies and X-ray microanalysis

et al. 1981

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Microscopic studies have been performed on skin biopsies from five patients with occupational argyria. Small brown-black granules were present in the dermis on light microscopy and were intensely refractile with dark-field illumination. Electron microscopy showed that the granules were electron-dense, round or oval in shape and varied in size from 30 nm to 100 nm. They were most numerous in relation to the basal lamina of the eccrine sweat glands, but were also present in relation to the basal lamina of the epidermis and dermal elastic fibres. X-ray microanalysis confirmed that many of the granules contained silver and sulphur. However, selenium, mercury, titanium and iron were also identified and it is probable that these elements were deposited in the skin also as a result of occupational exposure.

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Section: Electron Microscopymentioning

confidence: 56%

Occupational argyria; light and electron microscopic studies and X-ray microanalysis

et al. 1981

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“…53 Mercury is demonstrable as coarse, refractile brown-black granules within the papillary dermis. 54 Iron and melanin stains are negative. 11,51 The granules aggregate in macrophages and around capillaries as well as lying free in the dermis.…”

Section: Cutaneous Hyperpigmentationmentioning

confidence: 99%

Mercury exposure and cutaneous disease

Boyd

Seger²,

Vannucci³

et al. 2000

Journal of the American Academy of Dermatology

140

120

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“…Electron microscopy showed the granules to be small electron-dense particles appearing to aggregate into larger coarse granules with diameters up to 340 nm. 286 Mercury granulomas represent another manifestation of cutaneous mercury deposition. The causes may include accidental penetration as from a broken thermometer or from deliberate intradermal or subcutaneous injections.…”

Section: Mercurymentioning

confidence: 99%

Cutaneous Deposits

Molina-Ruiz

Cerroni

Kutzner

et al. 2014

The American Journal of Dermatopathology

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: The cutaneous deposition disorders are a group of unrelated conditions characterized by the accumulation of either endogenous or exogenous substances within the skin. These cutaneous deposits are substances that are not normal constituents of the skin and are laid down usually in the dermis, but also in the subcutis, in a variety of different circumstances. There are 5 broad categories of cutaneous deposits. The first group includes calcium salts, bone, and cartilage. The second category includes the hyaline deposits that may be seen in the dermis in several metabolic disorders, such as amyloidosis, gout, porphyria, and lipoid proteinosis. The third category includes various pigments, heavy metals, and complex drug pigments. The fourth category, cutaneous implants, includes substances that are inserted into the skin for cosmetic purposes. The fifth category includes miscellaneous substances, such as oxalate crystals and fiberglass. In this article, the authors review the clinicopathologic characteristics of cutaneous deposition diseases, classify the different types of cutaneous deposits, and identify all the histopathologic features that may assist in diagnosing the origin of a cutaneous deposit.

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Mercury pigmentation. An electron microscopic study

Cited by 13 publications

References 0 publications

Occupational argyria; light and electron microscopic studies and X-ray microanalysis

Occupational argyria; light and electron microscopic studies and X-ray microanalysis

Mercury exposure and cutaneous disease

Cutaneous Deposits

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