Mental Stress–Induced Myocardial Ischemia

Bravo, Paco E.; Cappola, Thomas P.

doi:10.1001/jama.2021.18766

Cited by 7 publications

(4 citation statements)

References 14 publications

(21 reference statements)

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“…Mental stress is also particularly strongly associated with cardiovascular disease 38 . For example, several articles have reported that mental stress induces myocardial ischemia in patients with coronary artery disease 39 , 40 and that depression is correlated with cardiovascular disease 41 . In addition, the Japan Collaborative Cohort Study for Evaluation of Cancer Risk (JACC study), which was sponsored by the Ministry of Education, Science, Sports and Culture of Japan, identified mental stress as being associated with increased coronary artery disease and increased stroke mortality in women 42 , and in the large-scale international case–control INTERHEART study, psychosocial factors were found to more than double the risk of myocardial infarction 43 .…”

Section: Discussionmentioning

confidence: 99%

Evaluation of the benefits of neutral bicarbonate ionized water baths in an open-label, randomized, crossover trial

Ushikoshi-Nakayama,

Yamazaki,

Omagari

et al. 2024

Sci Rep

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We previously demonstrated that neutral bicarbonate ionized water (NBIW) bathing enhances blood flow by bicarbonate ions and described the underlying mechanism. However, additional clinical investigation was warranted to investigate the efficacy of NBIW bathing. Hence, we performed a randomized, open-label, crossover trial to examine the effects of NBIW bathing on mental stress, sleep, and immune function. Participants who regularly felt stressed were randomly assigned to NBIW or regular bathing for 4 weeks. Mental stress was assessed with the Brief Job Stress Questionnaire (BJSQ) and the Profile of Mood States Second Edition; sleep quality, with the Pittsburgh Sleep Quality Index Japanese version (PSQI-J) and actigraphy; and immune function, with laboratory tests. PSQI-J scores and actigraphy sleep latency and bed out latency improved significantly more with NBIW bathing than with regular bathing (p < 0.05). Furthermore, NBIW bathing reduced both stress-induced fluctuations in CD4+ and CD8+ T cell counts and fluctuations in the naive to memory T cell ratio and neutrophil phagocytosis, indicating improved immune function. These findings suggest that daily NBIW bathing could improve mental stress, sleep quality, and immune function and bring about positive health effects in those who experience stress in their daily lives.

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Section: Discussionmentioning

confidence: 99%

Evaluation of the benefits of neutral bicarbonate ionized water baths in an open-label, randomized, crossover trial

Ushikoshi-Nakayama,

Yamazaki,

Omagari

et al. 2024

Sci Rep

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show abstract

“…26,27 Mental stress is also particularly strongly associated with cardiovascular disease. 28 For example, several articles have reported that mental stress induces myocardial ischemia in patients with coronary artery disease 29,30 and that depression is correlated with cardiovascular disease. 31 In addition, the Japan Collaborative Cohort Study for Evaluation of Cancer Risk (JACC study), which was sponsored by the Ministry of Education, Science, Sports and Culture of Japan, identi ed mental stress as being associated with increased coronary artery disease and increased stroke mortality in women, 32 and in the large-scale international case-control INTERHEART study, psychosocial factors were found to more than double the risk of myocardial infarction.…”

Section: Discussionmentioning

confidence: 99%

The Benefits of Neutral Bicarbonate Ionized Water Baths: An Open-Label, Randomized, Crossover Trial

Nakayama-Ushikoshi

Yamazaki

Omagari

et al. 2023

Preprint

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We performed a randomized, open-label, crossover trial to examine the effects of neutral bicarbonate ionized water (NBIW) bathing on mental stress, sleep, and immune function. Participants who regularly felt stressed were randomly assigned to NBIW or regular bathing for 4 weeks. Mental stress was assessed with the Brief Job Stress Questionnaire (BJSQ) and the Profile of Mood States Second Edition (Japanese version); sleep quality, with the Pittsburgh Sleep Quality Index (PSQI-J; Japanese version) and actigraphy; and immune function, with laboratory tests. PSQI-J scores and actigraphy sleep latency and bed out latency improved significantly more with NBIW bathing than with regular bathing (p < 0.05). Furthermore, NBIW bathing reduced both stress-induced fluctuations in CD4+ and CD8+ T-cell counts and fluctuations in the naïve to memory T cell ratio and neutrophil phagocytosis, indicating improved immune function. These findings suggest that NBIW bathing improves mental stress, sleep quality, and immune function.

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“…Moreover, stress causes a consistent elevation of blood pressure, thereby contributing to the development of hypertension [6]. Stress has also been implicated in increasing the risk of accelerating atherosclerosis and clinical cardiovascular events by precipitating myocardial infarction (MI) or causing myocardial injury and damage [7,8].…”

Section: Introductionmentioning

confidence: 99%

Effect of forest bathing (‘shinrin-yoku’) on human health – a literature review

Krala-Szkaradowska,

Stencel,

Skrzypczak

et al. 2024

Med Srod.

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Introduction and Objective.In contemporary times, stress is an inherent part of human life which can contribute to the development of many lifestyle diseases. Therefore, methods of coping with stress and strategies for preventing stress-related diseases have been long the focus of interest in the medical community. In recent times, there has been a surge in interest regarding the practice of 'shinrin yoku', also known as forest bathing. This practice entails walking or immersing oneself in a forested environment, actively engaging all sensory modalities in the perception of the surroundings. The purpose of this study is to investigate the effects of forest bathing on human health. Brief description of the state of knowledge. Forest bathing has been proven to have a positive impact on both mental and physical health. A decrease in cortisol levels in saliva and an increase in serotonin levels in the blood have been observed. Studies using a POMS questionnaire showed a reduction in levels of fatigue, tension, anger, and anxiety, along with increased vigour. Improvement in sleep quality was also noted. Forest bathing lowered blood pressure and heart rate while increasing Heart Rate Variability (HRV). The activity of NK cells in the immune system also increased. Summary. Based on a review of studies, forest bathing has a positive impact on human health. This practice can be utilized to reduce stress levels, enhance overall well-being and support the functioning of the immune system. Taking into consideration an individual approach to the patient, forest bathing can be one of the methods of preventive medicine, especially in the context of cardiovascular diseases and mental disorders, and can also support pharmacological therapy for conditions such as hypertension, depression, and sleep disorders. However, further research into this topic is needed.

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Mental Stress–Induced Myocardial Ischemia

Cited by 7 publications

References 14 publications

Evaluation of the benefits of neutral bicarbonate ionized water baths in an open-label, randomized, crossover trial

Evaluation of the benefits of neutral bicarbonate ionized water baths in an open-label, randomized, crossover trial

The Benefits of Neutral Bicarbonate Ionized Water Baths: An Open-Label, Randomized, Crossover Trial

Effect of forest bathing (‘shinrin-yoku’) on human health – a literature review

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