volume 93, issue 0, P3-P-307 2020
DOI: 10.1254/jpssuppl.93.0_3-p-307
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Abstract: It has been shown that the biological sex difference lies not only in gonadal functions but also in physiological or pathophysiological aspects of whole body, including drug efficacy, adverse effects, and pharmacokinetics. Particularly, women experience more adverse events than men. Although it is plausible that the higher risks of adverse events in women could be partly explained by lower renal excretion of drugs, the underlying mechanisms on the sex differences have not been elucidated yet. It is known both …

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