volume 137, issue 1-2, P38-51 2005
DOI: 10.1016/j.chemphyslip.2005.06.003
View full text
Sign up to set email alerts

Abstract: Subtilosin A is an antimicrobial peptide produced by the soil bacterium Bacillus subtilis that possesses bactericidal activity against a diverse range of bacteria, including Listeria monocytogenes. Recent structural studies have found that subtilosin A is posttranslationally modified in a unique way, placing it in a new class of bacteriocins. In this study, in order to understand the mechanism of membrane-disruption by subtilosin A, the interaction of the peptide with model phospholipid bilayers is characteriz…

Expand abstract