Membrana amniótica na reconstrução da superfície ocular após exérese de carcinoma de células escamosas da conjuntiva

Carvalho-rêgo, Paulo Roberto De; Gomes, José Álvaro Pereira; Ballalai, Priscilla Luppi; Cunha, Marcelo; Sousa, Luciene Barbosa de; Erwenne, Clélia Maria

doi:10.1590/s0004-27492008000100005

Cited by 4 publications

(3 citation statements)

References 22 publications

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“…When wide excisions are necessary for tumor surgery, autologous graft or labial mucosa can be used for surface reconstruction [1]. An alternative is the use of amniotic membrane graft, which has been used in ocular surface reconstruction in surgical scarring diseases of the cornea and conjunctiva [2,3,4,5,6,7,8]. The amniotic membrane is the innermost layer of the placenta and is a thick basal membrane with an avascular stroma [1].…”

Section: Introductionmentioning

confidence: 99%

“…The use of amniotic membrane as graft is appropriated due to its anti-inflammatory and anti-scarring effects. Amniotic membrane contains growth factors that promote epithelial wound healing on the surface of the eye, working as a basement membrane substitute or as a temporary graft [2]. …”

Section: Introductionmentioning

confidence: 99%

“…Although widely used in ophthalmic surgery, the use of sutures is time-consuming and increases tissue manipulation [2,3]. Sutures can cause tissue trauma, potential for granuloma formation and increased surgical time.…”

Section: Introductionmentioning

confidence: 99%

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Surgical Reconstruction of Ocular Surface Tumors Using Fibrin Sealant Tissue Adhesive

2016

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Purpose: To evaluate the surgical outcomes of ocular surface reconstruction in corneal-conjunctival tumors using fibrin tissue adhesive. Methods: A prospective noncomparative study was performed between May 2013 and February 2015. Patients were submitted to routine surgical procedure for corneal-conjunctival tumor excision followed by amniotic membrane graft transplantation using fibrin tissue adhesive (Evicel®, Omrix Biopharmaceuticals Ltd., Israel). Results were assessed on the 1st, 7th, 15th and 30th postoperative days to analyze subjective complaints, adhesiveness and positioning of the graft, potential complications and recurrences. Results: Twenty-five eyes were analyzed (male, 14). The diagnosis after the treatment was categorized as squamous cell neoplasia, dysplasia, actinic keratosis, squamous papilloma and compound melanocytic nevus. Few significant symptoms were reported, such as mild hyperemia and ocular dyscomfort. One case developed a conjunctival granuloma which regressed after topical treatment. All grafts were successful with no displacements or retraction postoperatively. There was no clinical recurrence of the tumor in a mean time of follow-up of 11 months. Conclusion: Fibrin tissue adhesive is safe and effective in the surgery of ocular surface tumor. In this series, sutureless amniotic membrane transplantation using fibrin glue has the potential to shorten the surgical time, mitigate inflammation postoperatively and improve patient discomfort.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Surgical Reconstruction of Ocular Surface Tumors Using Fibrin Sealant Tissue Adhesive

2016

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The Diagnostic Value of Exfoliative Cytology vs Histopathology for Ocular Surface Squamous Neoplasia

Semenova

Milman

Finger

et al. 2009

American Journal of Ophthalmology

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Conjunctiva Limbal Autograft with Fibrin Glue for Capillary Hemangioma

Sakarya

Özçimen

et al. 2015

Electron J Gen Med

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To present reversal of sensation of conjunctival limbal autograft. A 48-year-old female presented with red-colored mass in the left eye involving the temporal bulbar conjunctiva and limbus. It was vascular, elevated, compressible and immobile. Excisional biopsy, and conjunctiva limbal autgrafting with fibrin glue was performed, and histopathologic examination confirmed the diagnosis of capillary hemangioma of conjunctiva. Sensation of conjunctival autograft was measured at each month with Cochet-Bonnet esthesiometer for six months. Sensation of conjunctival autograft was none at first month and reached to normal level at fourth month. Conjunctiva limbal autograft with fibrin glue obtained good cosmesis for management of capillary hemangioma. Conjunctival autograft had no sensation at first month. Its sensation gradually increased and returned to normal level after 4 month.

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Membrana amniótica na reconstrução da superfície ocular após exérese de carcinoma de células escamosas da conjuntiva

Cited by 4 publications

References 22 publications

Surgical Reconstruction of Ocular Surface Tumors Using Fibrin Sealant Tissue Adhesive

Surgical Reconstruction of Ocular Surface Tumors Using Fibrin Sealant Tissue Adhesive

The Diagnostic Value of Exfoliative Cytology vs Histopathology for Ocular Surface Squamous Neoplasia

Conjunctiva Limbal Autograft with Fibrin Glue for Capillary Hemangioma

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