Melasma. Etiologic and therapeutic considerations

Grimes, Pearl E.

doi:10.1001/archderm.131.12.1453

Cited by 273 publications

(341 citation statements)

References 30 publications

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“…[59][60][61][62] Trata-se de doença dermatológica facilmente diagnosticada ao exame clínico, porém, apresenta uma cronicidade característica, com recidivas frequentes, grande refratariedade aos tratamentos existentes e ainda muitos aspectos fisiopatológicos desconhecidos. 57 O nome melasma deriva do grego melas, significando negro.…”

Section: Melasmaunclassified

“…Porém, parece que predisposição genética e exposição às radiações solares desempenham um papel importante, tendo em vista que as lesões de melasma são mais evidentes, durante ou logo após períodos de exposição solar. 7,60,62,63,[68][69][70] Sacre et al, investigando o melasma idiopático, concluiu que as reservas tireotrófica, prolactínica e gonadotrófica apresentaram-se normais e, como observou, as funções ovariana e tireoidiana, também, normais, logo, não foi possível estabelecer correlação entre os níveis hormonais encontrados e essa forma de melasma. 71 Ao contrário do que ocorre na gravidez, o melasma induzido por anovulatórios não involui com suspensão da droga e, entre as pacientes que o apresentaram pelos contraceptivos, 87% também o tinham manifestado em gestações anteriores.…”

Section: Melasmaunclassified

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Fisiopatologia do melasma

Miot¹,

Miot²,

Silva³

et al. 2009

An. Bras. Dermatol.

120

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Resumo: Melasma é uma dermatose comum que cursa com alteração da cor da pele normal, resultante da hiperatividade melanocítica focal epidérmica de clones de melanócitos hiperfuncionantes, com consequente hiperpigmentação melânica induzida, principalmente, pela radiação ultravioleta. Clinicamente, caracteriza-se por manchas acastanhadas, localizadas preferencialmente na face, embora possa acometer também região cervical, torácica anterior e membros superiores. Mulheres em período fértil e de fototipos intermediários representam as populações mais acometidas. Grande parte de sua fisiopatogenia permanece desconhecida, havendo relação com fatores genéticos, hormonais, uso de medicamentos, cosméticos, endocrinopatias e fotoexposição. Os autores discutem os principais elementos relacionados à pigmentação da pele e ao desenvolvimento do melasma. Palavras-chave: Melanose; Pigmentação da pele; Raios Ultravioleta; Transtornos da pigmentação Abstract: Melasma is a common dermatosis that involves changes in normal skin pigmentation, resulting from the hyperactivity of epidermal melanocytes. The consequent hyperpigmentation is mostly induced by ultraviolet radiation. Clinically, melasma is characterized by light to dark brown macules that usually occur on the face, although they can also affect the cervical and anterior thoracic regions and upper members. Fertile age women and those with intermediate skin phototypes are most likely to develop melasma. Most of its physiopathogenics is not yet fully understood, but there is a relation with genetic and hormonal factors, drugs and cosmetics use, endocrinopathies and sun exposure. The authors discuss the main aspects associated with skin pigmentation and the development of melasma.

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Section: Melasmaunclassified

Fisiopatologia do melasma

Miot¹,

Miot²,

Silva³

et al. 2009

An. Bras. Dermatol.

120

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“…However, levels of ²-melanocytic-stimulating-harmone have been found to be normal in idiopathic cases and those on oral contraceptive drugs [5,6]. Certain other factors like hepatic dysfunction, nutritional deficiencies and medications have been implicated [3,7]. Pathak et al [8] suggest that genetic influence and exposure to UV radiation are important.…”

Section: Introductionmentioning

confidence: 99%

IgM Chlamydia Trachomatis Antibodies in Cases of Melasma

Sawhney¹,

Batra

2005

Medical Journal Armed Forces India

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“…Most commonly affected areas include the forehead, upper lip, nose, and cheeks. The disease is often seen in women, however men are also likely to get it, too (1). Melasma usually appears among Asian women, who form almost one-third of all the women worldwide, and is more prevalent in Asian compared to Mediterranean women (2).…”

Section: Introductionmentioning

confidence: 99%

Nutritional Advice for Patients with Melasma in Iranian Traditional Medicine

et al. 2016

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Background: Melasma (called Kalaf in Iranian traditional medicine) is a common acquired hypermelanosis that affects sun-exposed areas of skin. Several factors including exposure to sunlight, pregnancy, and endocrine diseases increase the risk for Melasma. In traditional medicine, antecedent philosophers and physicians have tried to understand the nature and mechanisms of different systems of the human body for the diagnosis and management of Melasma; they have offered different solutions for it. This study is important since Melasma is a disease causing mental side effects in patients, due to darkness and opacity of the skin; therefore, the treatment of Melasma in terms of its psychological complications is of particular importance. In addition, texts of Iranian traditional medicine contain a wealth of nutritional advice for patients with Melasma. These texts have, until now, not yet been reviewed. The present study has considered the most important references of Iranian traditional medicine texts. Objectives: The objective of this study was to extract and categorize the nutritional advice of Iranian traditional medicine texts for the treatment of Melasma. Results: Dietary recommendations, not only for treatment but also for prevention of diseases and staying healthy, are very efficient. Conclusions: Based on the traditional medicine texts, it is helpful to avoid Soda-producing food as well as to identify appropriate food in order to eliminate the accumulation of Soda or black bile from the blood. This study offers a set of analytical and clinical research on food, which in traditional medicine is called Soda-producing as well as Soda reducing.

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Melasma. Etiologic and therapeutic considerations

Cited by 273 publications

References 30 publications

Fisiopatologia do melasma

Fisiopatologia do melasma

IgM Chlamydia Trachomatis Antibodies in Cases of Melasma

Nutritional Advice for Patients with Melasma in Iranian Traditional Medicine

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