1938
DOI: 10.1001/archderm.1938.01480160066007
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Melanotic Sarcoma With Extreme Melanosis

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1953
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Cited by 15 publications
(6 citation statements)
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“…Since that time a number of eases have been described jn which the hyperpigmentation resulted from widespread dissemination melanoma cells (Dawson 1925, Way & Light 1930. These differ from the true cases of melanosis in whieh an overall effect on the pigmentary system results in deposition of pigment mainly in dermal melanophages (Albertini & Walthard 1927, Odel et al 1937, Dixon 1938, Trueblood 1947, Albeaux-Femet et al 1949, Ritz 1949, Fitzpatriek et al 1954, Moller 1954, Goodall et al 1961, Silberberg et al 1968, Sohn et al 1969, Kint et al 1973, Holcomb et al 1975, Bork et al 1977. The interesting case deseribed by Konrad & Wolff in 1974 appears to be distinct from either of the above categories in that the dissemination of melanoma cells was extensive but did not merely involve multiple nodules.…”
Section: Discussioncontrasting
confidence: 53%
“…Since that time a number of eases have been described jn which the hyperpigmentation resulted from widespread dissemination melanoma cells (Dawson 1925, Way & Light 1930. These differ from the true cases of melanosis in whieh an overall effect on the pigmentary system results in deposition of pigment mainly in dermal melanophages (Albertini & Walthard 1927, Odel et al 1937, Dixon 1938, Trueblood 1947, Albeaux-Femet et al 1949, Ritz 1949, Fitzpatriek et al 1954, Moller 1954, Goodall et al 1961, Silberberg et al 1968, Sohn et al 1969, Kint et al 1973, Holcomb et al 1975, Bork et al 1977. The interesting case deseribed by Konrad & Wolff in 1974 appears to be distinct from either of the above categories in that the dissemination of melanoma cells was extensive but did not merely involve multiple nodules.…”
Section: Discussioncontrasting
confidence: 53%
“…Increased amounts of melanin in the keratinocytes of the basal and lower malpighian layer of the epidermis, associated with a normal number of melanocytes, are inconstant features, and have been ascribed to an epithelial growth disturbance, or hormonal changes (Odel et al 1937, Dixon 1938, Albeaux-Fernet et al 1949, Silberberg et al 1968, Sohn et al 1969, Bork et al 1977. Decreased epidermopoiesis due to chemotherapeutic agents was suggested by Silberberg et al as one alternative reason for the increased epidermal pigmentation in his case, and it is interesting to note that, in our patient, the amount of melanin in the epidermis seemed normal even though cytotoxic treatment had started three weeks before death.…”
Section: Discussionmentioning
confidence: 99%
“…The reticuloendothelial cells of the liver and spleen (Albertini et al 1927, Dixon 1938, Ritz 1949, Goodall et al 1961, Sohn et al 1969, bone marrow (Albertini et al 1927, Goodall et al 1961) and lymph nodes (Albertini et al 1927, Dixon 1938, Goodall et al 1961, Sohn et al 1969, are loaded with pigment, and various parenchymal cells, such as renal tubular cells (Albertini et al 1927, Way et al 1930, Dixon et al 1938, Ritz 1949, Goodall et al 1961, Sohn et al 1969, thyroid cells (Goodall et al 1961), and adrenals (Goodall et al 1961, Sohn etal. 1969, may contain melanin granules.…”
Section: Discussionmentioning
confidence: 99%
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“…DIFFUSE MELANOSIS is a rare, but well‐recognized complication of metastatic melanoma. To date, 36 cases have been reported in the world literature 1–36 . The first reported case of diffuse melanosis was described by Legg in 1884 1 .…”
mentioning
confidence: 99%