Mélano-acanthome

Delacrétaz, J.

doi:10.1159/000251341

Cited by 18 publications

(5 citation statements)

References 3 publications

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“…[12] The transfer of melanin from these highly dendritic melanocytes to mature keratinocytes is often partially blocked, though in some cases nearly all the melanin is retained in the melanocytes. [17,18] It is also interesting to mention that in our patient, one of the plaques of melanoacanthoma was ulcerated. To the best of our knowledge, ulceration in melanoacanthoma has not been reported previously in the literature.…”

Section: Discussionmentioning

confidence: 58%

Multifocal cutaneous melanoacanthoma with ulceration: A case report with review of literature

Jain¹,

Barman²,

Garg³

et al. 2011

Indian J Dermatol Venereol Leprol

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We report a case of a 58-year-old female patient who presented with multiple, asymptomatic, slowly-growing, raised pigmented lesions all over her body for the past 10 years with ulceration in one of the lesions on the trunk for the past five months. Histopathology of the lesion revealed features consistent with melanoacanthoma. Here, we report the first case of cutaneous melanoacanthoma presenting with an ulcerated plaque and the third case of cutaneous melanoacanthoma with multiple lesions. To the best of our knowledge, ulceration has not yet been reported as a feature of cutaneous melanoacanthoma in the medical literature.

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Section: Discussionmentioning

confidence: 58%

Multifocal cutaneous melanoacanthoma with ulceration: A case report with review of literature

Jain¹,

Barman²,

Garg³

et al. 2011

Indian J Dermatol Venereol Leprol

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“…[ 3 ] This neoplasm represents a slowly growing, usually solitary, growth of head and neck, or trunk, of older people. [ 4 – 6 ] Melanoacanthoma clinically simulate seborrheic keratosis or a melanoma and may attain a diameter of 3 cm or more. [ 7 ] According to the current view, melanoacanthoma denotes a rare variant of seborrheic keratosis rather than a distinct entity,[ 2 ] that differs from the usual type of pigmented seborrheic keratosis by marked increase in the concentration of melanocytes.…”

Section: Introductionmentioning

confidence: 99%

Giant melanoacanthoma mimicking malignant melanoma

et al. 2011

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Melanoacanthoma denotes a rare variant of pigmented seborrheic keratosis. A 65-year-old male farmer had pigmented, verrucous, itchy, highly painful, progressively growing irregularly oval plaque on left side of lower back for the past five years. The indurated lesion, measuring maximum diameter 10 cm × 5 cm, had no discharge, bleeding, ulceration, or associated lymphadenopathy. Dermoscopy showed regular pigmentary network and cribiform pattern of ridges without any feature of malignant melanoma. Histopathology showed well-defined islands of basaloid cells interspersed with large and richly dendritic melanocytes. The lesion was totally excised followed by skin grafting. Our patient was unique in its massive size and clinical resemblance with malignant melanoma. The diagnosis was confirmed by dermoscopy and skin biopsy.

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“…Melanoacanthoma has been described once previously on the eyelid, occurring in a 40‐year‐old black man as multiple, minute, individual and confluent, dark, shiny papules limited in distribution to the left upper eyelid 3 . Cutaneous melanoacanthoma is usually evident as a single, pigmented, verrucous, round or oval plaque with a diameter ranging from a few millimeters to 10 cm 4–14 . Cutaneous melanoacanthomas are mainly found on the head, particularly the lips, and the trunk.…”

Section: Discussionmentioning

confidence: 99%

Giant cutaneous melanoacanthoma

et al. 2004

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A 45‐year‐old male cook was seen for the evaluation and removal of a “mole on my eye” of steady growth during the previous 6 months. The patient stated that he had had a “brown spot” above his left eye for 17 years prior to its recent enlargement; it was now partly blocking the vision in his left eye. He denied a history or family history of cutaneous tumors, including skin cancer. On examination, a 2.5‐cm × 0.5‐cm × 0.8‐cm, horn‐like, darkly pigmented, cutaneous nodule was evident extending from the left upper eyelid downwards to below the lower eyelid (Figs 1 and 2). He also had scattered, skin‐colored, 2–3‐mm cystic papules on his anterior mid‐chest. A shave excision specimen was obtained from the eyelid nodule. 1 Horn‐like, cutaneous nodule extending from the left upper eyelid downwards to below the lower eyelid 2 Close up, demonstrating the morphologic features to better advantage Microscopic examination demonstrated acanthosis, hyperkeratosis, and papillomatosis (Fig. 3). Large dendritic cells with abundant melanin granules were spread throughout the epidermis. In addition, small basaloid or spinous keratinocytes were present in the malpighian layer. 3 Histology of the nodule, showing an epidermis with acanthosis, hyperkeratosis, papillomatosis, and large dendritic cells with abundant melanin granules spread throughout the epidermis (hematoxylin and eosin; original magnification, × 100)

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Mélano-acanthome

Cited by 18 publications

References 3 publications

Multifocal cutaneous melanoacanthoma with ulceration: A case report with review of literature

Multifocal cutaneous melanoacanthoma with ulceration: A case report with review of literature

Giant melanoacanthoma mimicking malignant melanoma

Giant cutaneous melanoacanthoma

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