Medicinal Plants in Basic Care: A Study of Clinical Practice

Souza, Carlos Adriano Santos; Andrade, Wesley M.G.; Ramos, Thaís S.; Filho, Alex José Silveira; Freitas, Anderson Leite; Lima, Tamires Cardoso; Antoniolli, Ângelo Roberto; Silva, Wellington B.; Silva, Francilene A.

doi:10.5530/pj.2019.11.127

Cited by 2 publications

(1 citation statement)

References 19 publications

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“…These advantages are: high pharmacotherapeutic efficacy of herbal remedies, low toxicity or lack thereof, mild action, which determines the possibility of their long-term use without the risk of adverse reactions. 1,2 Inulin and fructooligosaccharides (fructosides of various polymerization degrees) are reserve polysaccharides of some plants, actively used in both the pharmaceutical and food industries; they are utilized in the production of biologically active additives and drugs. They can positively affect the metabolism, activate the pancreas function, stabilize blood glucose levels, promote the excretion of heavy metals salts and the absorption of calcium, iron, as well as provide hypocholesterolemic, immunomodulating and prebiotic effects.…”

Section: Introductionmentioning

confidence: 99%

Pharmacopoeial Analysis of Inulin-Containing Medicinal Plant Raw Materials and Drugs

Di¹,

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et al. 2020

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Different types of search tools such as Google scholar, Google, scientific literature, normative documentation of Russian Federation (State Pharmacopoeia of Russian Federation IV edition and others) electronic databases such as e-Library, Scopus, Web of Science, Pubmed had been searched and data obtained. RESULTS AND DISCUSSION Characterization of polyfructans Fructooligosaccharides (FOS) (oligofructose)-a mixture of oligomers, which contain from 1 to 7 moieties of D-fructose, and as a rule, terminal D-glucose. FOS is obtained in two ways: by splitting inulin and by enzymatic transfer of fructose to sucrose (transfructosylation). Oligofructose, like inulin, belongs to water-soluble dietary fiber and is prebiotic, and a mixture of these compounds, which is also often called fructooligosaccharides, has more effective prebiotic properties. Polyfructans (fructosans, Pfrus) are carbohydrate polymers formed by a sucrose molecule, an extended chain of fructose moieties. In nature, Pfrus are found in bacteria, fungi, and plants in which they perform various ABSTRACT Background: Today, there are some unresolved issues and discussions concerning inulin quantitative determination in medicinal plant raw materials (MPRM). MPRM containing polyfructans or fructosans (inulin and others) are rather complex multicomponent matrixes with many interacting compounds. The article discusses the prospects for further standardization of inulin-containing pharmacopoeial MPRM that include, in addition to polysaccharides (inulin), other biologically active compounds with pharmacological activity. Materials and Methods: Different types of search tools such as Google scholar, Google, scientific literature, normative documentation of Russian Federation (State Pharmacopoeia of Russian Federation IV edition and others) electronic databases such as e-Library, Scopus, Web of Science, Pubmed had been searched and data obtained. Results: The pharmacopoeial spectrophotometric procedures of inulin determination in the Russian Federation are approved in a version that does not fully satisfy modern standardization criteria. Regulatory changes required in the near future. Conclusion: Undoubtedly, to determine inulin quantitatively, it is necessary to modify the existing spectrophotometric procedures and introduce an additional alternative, more specific HPLC-RID (or similar) ones.

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Section: Introductionmentioning

confidence: 99%