Medication-Adherence and Management of Risk Factors for Secondary Prevention of Stroke Using Smartphone-Based Application

Babu, Veena; Sylaja, P N; Soman, Biju; Varma, Ravi Prasad; Manju, M S; Geethu, G L; Kumar, B Suresh

doi:10.4103/aian.aian_836_22

Cited by 2 publications

(2 citation statements)

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“…The study is registered in clinical trial registry of India prior to the beginning of the study (CTRI/2022/06/042980) and protocol has been published. 18 Written informed consent was obtained from each participant, and they were free to withdraw from the study at any point.…”

Section: Methodsmentioning

confidence: 99%

A randomized controlled trial of medication adherence and management of risk factors for secondary prevention of stroke (MaMoRS) using a smartphone-based application

Babu,

Sylaja,

Soman

et al. 2024

International Journal of Stroke

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Background: There is little data on the use of smartphone-based applications for medication adherence and risk-factor control for the secondary prevention of stroke in low-and-middle-income countries (LMIC). Aims: To determine whether a smartphone-based app improved medication adherence, risk-factor control, and provided health education to stroke survivors for lifestyle and behavioural modifications. Methods: An unblinded, single-centre randomized controlled double arm trial with 1:1 allocation among stroke survivors was performed in South India. The primary outcome was medication adherence, with co-primary outcomes of lifestyle and behavioural factors and control of vascular risk factors, at three and six months. Results: Among 351 stroke survivors screened, 209 were recruited. The mean (SD) age of the intervention(n=105) group was 60(12) years and that of the control (n=104) group was 60(10) years. The primary outcome, mean medication adherence significantly improved in the intervention group with a between group difference of 0.735(95% CI:0.419-1.050), p<0.001. Being in intervention group (OR=4.5; 95% CI:2.3-8.9), stroke recurrence (OR=3.3(95% CI:1.9-7.8), and regular physician visits (OR=2.1; 95% CI:1.0–4.4) were significant predictors of good medication adherence. Considering the co-primary outcomes, compared to the control group, participants in the intervention group had a greater improvement in self-reported healthy diet intake (p=0.003), intake of fruits (p=0.005), and were physically more active (p=0.001). At six months mean fasting blood sugar (p=0.005) and high-density lipoprotein cholesterol higher (p=0.024) in the intervention group. Conclusions: The use of a mobile app is an effective method to improve medication adherence and risk- factor control in stroke survivors, and is feasible in LMICs like India. Data access statement: Data used during the study are available from the corresponding author on request. Trial registration: The study is registered in Clinical Trial Registry of India (CTRI/2022/06/042980).

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Section: Methodsmentioning

confidence: 99%

A randomized controlled trial of medication adherence and management of risk factors for secondary prevention of stroke (MaMoRS) using a smartphone-based application

Babu,

Sylaja,

Soman

et al. 2024

International Journal of Stroke

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“…It provides health education materials, reminders and physician intervention for effective secondary stroke prevention. 101…”

Section: Artificial Intelligence (Ai) and Digital Advancement For Strokementioning

confidence: 99%

Expert Consensus on Improving Stroke Care Ecosystem in India

Srivastava,

Mehndiratta,

Kaul

et al. 2024

Journal of Stroke Medicine

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The stroke burden in India is alarmingly high compared to Western industrialised countries, necessitating immediate action to develop stroke systems of care. Tailored stroke-prevention strategies, adequate resource allocation for stroke management and research, and increased awareness of specialised care in acute Stroke are critical. The COVID-19 pandemic has underscored the need for improved healthcare delivery and infrastructure. To address the rising stroke burden in India, comprehensive strategies encompassing prevention, awareness, specialised care and governmental support are urgently required. While the concept of ‘stroke-ready centres’ has emerged, their limited availability hinders widespread benefits. This expert consensus examines the current state of stroke care in India, identifies challenges, and proposes strategies to enhance stroke care systems. It offers valuable insights into stroke management at different levels, empowering healthcare professionals and administrators to assess their existing systems and make necessary improvements. Special attention is given to the role of physicians, including the use of thrombolytic therapies like Tenecteplase, in reducing the stroke burden and improving outcomes across the country. Significant strides can be made in stroke management and care in India by addressing these critical areas.

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Medication-Adherence and Management of Risk Factors for Secondary Prevention of Stroke Using Smartphone-Based Application

Cited by 2 publications

References 10 publications

A randomized controlled trial of medication adherence and management of risk factors for secondary prevention of stroke (MaMoRS) using a smartphone-based application

A randomized controlled trial of medication adherence and management of risk factors for secondary prevention of stroke (MaMoRS) using a smartphone-based application

Expert Consensus on Improving Stroke Care Ecosystem in India

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