Mediastinal lymphadenopathy and undifferentiated connective tissue disease: case report and review

Gordonson, J; Quinn, Michael; Kaufman, Raymond H.; Tweel, Jan G. van den

doi:10.2214/ajr.131.2.325

Cited by 10 publications

(3 citation statements)

References 14 publications

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“…The negative culture for tuberculosis and negative stains for malignancies indicated a rheumatoid nodule. Mediastinal lymphadenopathy is a common finding at autopsy in systemic lupus erythematosus and rheumatoid arthritis, but has seldom been mentioned in reports of rheumatic diseases except in Sjogren's syndrome 12. Rheumatoid nodules in mediastinal lymph nodes are extremely uncommon; however, they are nowadays more recognised thanks to the emergency of new technologies with better sampling such as endobronchial ultrasound-guided transbronchial needle aspiration and endoscopic ultrasound 13.…”

Section: Discussionmentioning

confidence: 99%

A rheumatoid nodule in an unusual location: mediastinal lymph node

2013

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Rheumatoid arthritis (RA) is a multisystem inflammatory disease characterised by destructive synovitis and varied extra-articular involvement. Rheumatoid lung nodules are the most common pulmonary manifestations of RA. Rheumatoid nodules in mediastinal lymph nodes are extremely uncommon. We describe a male patient with long-standing RA and subcutaneous rheumatoid nodules presenting with multiple lung nodules and mediastinal lymphadenopathies. Definite histopathology of a lymph node was consistent with necrobiotic granuloma due to RA. Clinicians should be aware of rheumatoid nodules as a potential cause of mediastinal lymphadenopathies, mainly in advanced rheumatoid arthritis.

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Section: Discussionmentioning

confidence: 99%

A rheumatoid nodule in an unusual location: mediastinal lymph node

2013

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“…25 In two patients with MCTD, mediastinal lymphadenopathy has been described. 44,45 Biopsy of the enlarged lymph nodes showed nonspecific lymphoid reaction.…”

Section: Mediastinal Lymphadenopathymentioning

confidence: 99%

Pulmonary Manifestations in Mixed Connective Tissue Disease

Prakash¹

1988

Semin Respir Crit Care Med

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“…Gordonson J and associates,[25] first described a patient with mediastinal lymphadenopathy and undifferentiated connective tissue disease. The histology of the lymph node showed follicular hyperplasia with plasmacytosis, a finding seen in rheumatoid arthritis.…”

Section: Introductionmentioning

confidence: 99%

Pictorial review of intrathoracic manifestations of progressive systemic sclerosis

et al. 2014

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Intra-thoracic manifestations of progressive systemic sclerosis (PSS) are not well known particularly the imaging features, which forms the basis of accurate and timely diagnosis. The aim of this study is to familiarize the physicians and radiologists with these features. The diagnosis can remain elusive because of the non-specific nature of symptoms which mimic many common conditions. Thus, the diagnosis of PSS can be missed leading to continuous morbidity if the correct imaging is not pursued. The authors examined the records of rheumatology patient referrals of over a 5 year period. A hundred and seventy patients with systemic sclerosis and mixed connective tissue disorders were chosen for detailed study of the imaging available, which form the basis of this review. The images included conventional chest radiographs, digital radiographs computed radiography (CT) and high resolution computed tomography (HRCT). Where applicable computed pulmonary angiography (CTPA) and radionuclide scans were also interrogated.

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Mediastinal lymphadenopathy and undifferentiated connective tissue disease: case report and review

Cited by 10 publications

References 14 publications

A rheumatoid nodule in an unusual location: mediastinal lymph node

A rheumatoid nodule in an unusual location: mediastinal lymph node

Pulmonary Manifestations in Mixed Connective Tissue Disease

Pictorial review of intrathoracic manifestations of progressive systemic sclerosis

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