Media Matters: Culture Medium-Dependent Hypervariable Phenotype of Mesenchymal Stromal Cells
Joan C. Fitzgerald,
Georgina Shaw,
J Mary Murphy
et al.
Abstract:Background
Despite a long history of investigation and sustained efforts in clinical testing, the number of market authorisations for mesenchymal stromal cell (MSC) therapies remains limited, with none approved by the United States Food and Drug Administration (FDA). Several barriers are impeding the clinical progression of MSC therapies, to the forefront of these is a lack of standardised manufacturing protocols which is further compounded by an absence of biologically meaningful characterisation and releas… Show more
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