Meconium and its Significance and Obstetric Outcome

Soni, Anjali; Vaishnav, Gunvant; Gohil, J. T.

doi:10.5455/medscience.2014.03.8183

Cited by 11 publications

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“…Birth weight for gestational age is a commonly assessed perinatal outcome parameter and Small for Gestational Age (SGA) defined as weighing less than 10th percentile of birth weight for that gestation is also an indicator for Intrauterine Fetal Growth Restriction (IUGR), its importance is due to high associated perinatal and infant morbidity and mortality as well as future adult chronic non-communicable diseases such as cardiovascular disease, stroke, type II diabetes, obesity, other endocrine and metabolic disorders prominently linked to Small for Gestational Age (SGA) [115,116]. Invalidating international reference WHO percentile intrauterine growth curves which differs from the Indian intrauterine growth curves such that the 10 th percentile is almost 800 g below WHO 10 th percentile curve, while 50 th percentile South Indian curve corresponds to 10 th percentile WHO curve, that would mistakenly identify a large proportion of Appropriate for Gestational Age (AGA) Indian babies as small for Gestation Age (SGA) who have differing morbidity and mortality, emphasizing further why ethnic Asians require specific intrauterine growth charts to avoid inaccurate labeling of SGA newborns and their management, however these small for dates after birth feed avidly and gain weight [104,107,108,112].…”

Section: Lnr Includes 3 Stepsmentioning

confidence: 99%

“…Thus the small Asian neonate with average low birth weight around 2800 -3000 g attributed to asymmetrical intrauterine growth retardation due to inherent genetic predisposition rather than environmental factors with low energy reserves are less well equipped to cope with any asphyxial insults resulting from uterine contractions especially when labor is prolonged with increased mortality and morbidity with adverse long term sequelae [101,104,115,129]. However healthy small for dates, shortly after birth, will feed avidly and gain weight indicating effective preventive strategies now takes on priority in saving the small Asian babies, that mandates institution of new ethnic Asian specific guidelines for well-being of Asian newborns by clinical implementation of peak ethnic Asian births with Asian Due Date (ADD) for delivery at 38+6 weeks gestation, thus preventing hypoxial birth injury and colossal asphyxial deaths which are totally preventable [101,104,107].…”

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Lalana Newborn Resuscitation

Christopher¹

2021

JCMR

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Section: Lnr Includes 3 Stepsmentioning

confidence: 99%

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confidence: 99%

Lalana Newborn Resuscitation

Christopher¹

2021

JCMR

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“…7 Many studies have shown that MSAF is associated with a high risk of fetal distress, operative delivery, and increased incidence of perinatal morbidity and mortality. [7][8][9] COVID-19-positive laboring mothers have a higher risk of having MSAF (23.63%), babies born with respiratory distress (10.5%), moderate-to-severe hypoxic ischemic encephalopathy (HIE) (3.6%), and sepsis (7%). 10 Increased risk of low birth weight of 14.3% and intrauterine growth restriction (IUGR) is also common.…”

Section: Introductionmentioning

confidence: 99%

Frequency of Meconium-stained Amniotic Fluid in COVID-positive Term Pregnancies and Perinatal Outcome

Anitha¹,

Tejeswini²,

Chetan³

et al. 2022

Journal of South Asian Federation of Obstetrics and Gynaecology

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Aim: To know the frequency of meconium-stained amniotic fluid (MSAF) among COVID-positive term pregnant mothers and to know perinatal outcomes in these neonates. Materials and methods: A retrospective study was conducted of COVID-positive term pregnancies admitted to Vanivilas hospital, Bangalore Medical College, during the study period of 1 year. The study period was from 1st of July 2020 to 31st of June 2021. High-risk pregnancies that confound the occurrence of MSAF were excluded (obstetric risk factors and medical risk factors complicating pregnancy). Data were collected from medical records of patients and parturition register, which are cross-verified with operation theater records and neonatal intensive care unit (NICU) registers. Results: In total, 200 pregnant women were included in the study. About 65% were delivered by cesarean, 34.5% by the vaginal route, and one vacuum-assisted delivery. In total, 199 live births and one fresh stillbirth are reported. About, 26% had MSAF and 6.5% of newborns had meconium aspiration syndrome. Grade I, II, and III cases were 4.5%, 12.5%, and 9% respectively. Low appearance, pulse, grimace, activity, and respiration (APGAR) scores were correlating with the grade of MSAF, which is statistically significant. There were two neonatal deaths in grade III MSAF cases. Conclusion:The frequency of MSAF is increased among COVID-positive mothers, which translates to low APGAR scores and poor perinatal outcomes. Vigilant intrapartum care is recommended for these pregnancies to reduce the risk of poor neonatal outcomes. Clinical significance: The current study is undertaken to know if coronavirus disease-2019 (COVID-19) is associated with an increased frequency of MSAF among COVID-positive pregnant women. Finding MSAF has implications on operative delivery, cesarean rates, and perinatal outcome. There is a lack of studies about MSAF and perinatal outcomes in COVID-positive mothers. Evidence generated by this study helps to counsel the COVID-positive mothers and guides in the management of COVID-positive laboring women.

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“…The literature shows that increased gestation period increases the incidence of meconium stained liquor rate. Evidence suggests that meconium stained liquor complicate the pregnancy (7% to 22%) 5 .…”

Section: Introductionmentioning

confidence: 99%

Frequency of meconium stained liqour in patients with postdates pregnancy

Mazhar

Arif²,

Jabeen³

2021

JMS

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ABSTRACT Objective To determine the frequency of meconium stained liqour in patients having gestation period of more than 40 weeks. Material and Methods This is a retrospective chart review of 495 patients treated at Khyber Teaching Hospital Peshawar Pakistan from September 2017 to September 2019. All the cases were identified from the medical record maintained at the Department. Laboring women having gestational age of more than 40 weeks were included in the study. Results A total of 495 patients were included in the study. The Frequency of meconium stained remained high (67.47%). Mean gestational age was 40 weeks with the SD of ± 1.084 weeks. With Primis (39.2%) and multis (60.8%), incidence of spontaneous labour was high (60%) as compared to induced labour (39.5%). Presence of meconium and fetal distress lead to high number of cesarean deliveries (64%). Out of total cases (334) delivered with meconium stained liquor, majority of cases (76%) were of grade 3MSL (39.5%) and grade 2 MSL (36.5%) respectively. 63.7% of cases led to cesarean deliveries. Conclusion Postdates pregnancy is a key factor causing meconium stained liqour. Timely induction of labour at 41 weeks of gestation is advised. Keywords Meconium stained liquor, postdates pregnancy, Meconium aspiration syndrome.

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Meconium and its Significance and Obstetric Outcome

Cited by 11 publications

References 0 publications

Lalana Newborn Resuscitation

Lalana Newborn Resuscitation

Frequency of Meconium-stained Amniotic Fluid in COVID-positive Term Pregnancies and Perinatal Outcome

Frequency of meconium stained liqour in patients with postdates pregnancy

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