Mechanistic Prediction and validation of Brevilin A Therapeutic Effects in Lung Cancer
Ruixue Wang,
Cuiyun Gao,
Meng Yu
et al.
Abstract:Background
Traditional Chinese medicine (TCM) has found widespread application in neoplasm treatment, yielding promising therapeutic candidates. Previous studies have revealed the anti-cancer properties of Brevilin A, a naturally occurring sesquiterpene lactone derived from Centipeda minima (L.) A.Br. (C. minima), a TCM herb, specifically against lung cancer. However, the underlying mechanisms of its effects remain elusive. This study employs network pharmacology and experimental analyses to unravel the molec… Show more
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