Biochemical Pharmacology volume 82, issue 8, P996-1007 2011 DOI: 10.1016/j.bcp.2011.07.075 View full text
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Michael Paolini, Mariella De Biasi

Abstract: Smoking is responsible for over 400,000 premature deaths in the United States every year, making it the leading cause of preventable death. In addition, smoking-related illness leads to billions of dollars in healthcare expenditures and lost productivity annually. The public is increasingly aware that successfully abstaining from smoking at any age can add years to one’s life and reduce many of the harmful effects of smoking. Although the majority of smokers desire to quit, only a small fraction of attempts t…

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