Mechanisms of Retraction Pocket Formation in the Pediatric Tympanic Membrane

Transmeatal excision of pars tensa retraction pockets with simultaneous ventilation tube insertion in children: a prospective study

“…Similar distributions were reported by Blaney et al (97%) and by Walsh et al (91%) whereas that described by Ars was lower (60%) [9][10][11]. The histopathological studies carried out by Ruah et al [12] demonstrated the persistence of mesenchyme (normally resorbed at 2 months of age) in the posterior quadrants for up to 3 years. There is merely poor elastin in this area, leaving a weaker TM once this mesenchyme finally disappears.…”

Quantitative Analysis of Tympanic Membrane Disease Using Video‐Otoscopy

“…Persistence of mesenchyme and a greater inflammatory reaction in the pars flaccida and the posterosuperior quadrant of the pars tensa have been found in purulent and serous otitis media in temporal bones of children between 2 days and 3 years of age. 13 In the present study, we found the anteroinferior quadrant of the pars tensa to be most frequently involved by tympanosclerosis. However, the extent of tympanosclerosis involvement was greatest in the posteroinferior quadrant.…”

Tympanic Membrane Retractions in patients with Williams Syndrome: A Controlled Study

“…Ruah et al considered that the delay in absorption and differentiation of the mesenchymal could be responsible for the inability of elastin fibers in the tympanic membrane to mature, and that this delay could be a risk factor to encourage the development of retraction pockets as soon as the mattress mesenchymal disappeared. 6 However, based on our findings, it seems that the elastin factor alone is not a risk factor for tympanic retractions.…”