Mechanics of the respiratory system in healthy newborn calves using impulse oscillometry

Uystepruyst, Christophe; Reinhold, Petra; Coghe, J.; Bureau, Fabrice; Lekeux, Pierre

doi:10.1053/rvsc.1999.0337

Cited by 13 publications

(12 citation statements)

References 38 publications

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“…The IOS is therefore quicker, potentially more informative and, owing to its more compact size and simpler calibration, could more readily be applied to field clinical testing than the previously described PFT. The IOS has already been validated in children (Klug 1997) and calves (Reinhold et al 1998a,b;Uystepruyst et al 2000) and proved to be a more sensitive method in comparison to plethysmography and spirometry (Bisgaard and Klug 1995). Because of its important technical advantages and potential improvement of PFT in the equine species, an evaluation of the application of the IOS in horses seemed particularly interesting.…”

Section: Introductionmentioning

confidence: 99%

Measurement of respiratory function by impulse oscillometry in horses

Erck

Votion

Art

et al. 2004

Equine Veterinary Journal

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Reasons for performing study: Due to technical implementations and lack of sensitivity, pulmonary function tests are seldom used in clinical practice. Impulse oscillometry (IOS) could represent an alternative method. Objectives: To define feasibility, methodology and repeatability of IOS, a forced oscillation technique that measures respiratory resistance (Rrs) and reactance (Xrs) from 5 to 35 Hz during spontaneous breathing, in horses. Methods: Using 38 healthy horses, Rrs and Xrs reference values were defined and influence of individual biometrical parameters was investigated. In addition, IOS measurements of 6 horses showing clinical signs of heaves were compared to those of 6 healthy horses. Results: Airtightness and minimal dead space in the facemask were prerequisites to IOS testing and standardisation of head position was necessary to avoid variations in Rrs due to modified upper airway geometry. In both healthy and diseased animals, measurements were repeatable. In standard‐type breeds, the influence of the horse's size on IOS parameters was negligible. An increase in R5Hz greater than 0.10 kPa/l/sec and R5Hz>R10Hz, combined with negative values of Xrs between 5 and 20 Hz, was indicative of heaves crisis. Conclusions: IOS is a quick, minimally invasive and informative method for pulmonary function testing in healthy and diseased horses. Potential relevance: IOS is a promising method for routine and/or field respiratory clinical testing in the equine species.

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Section: Introductionmentioning

confidence: 99%

Measurement of respiratory function by impulse oscillometry in horses

Erck

Votion

Art

et al. 2004

Equine Veterinary Journal

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“…According to Dean [48], the position of the neonate influences the intensity of the respiratory activity immediately post natum. Likewise, in this context, the published results of Uystepruyst and colleagues [30] indicate the importance of postnatal lying position. Resistance and reactance depend on the position of bovine neonates.…”

Section: Discussionmentioning

confidence: 84%

“…Although Cassin et al [8] have found that in sheep fetuses the lung resistance gradually decreases until birth, which correlates with increased metabolism and growth expression of lung tissue, it can be assumed that immediately post natum the minimum value is not yet reached [49]. The work of Varga et al [43] and Uystepruyst and coauthors [30] points out that according to their measurements with a pulse oscillation system (IOS) in bovine neonates within the first hours reveal an increased resistance value (R5HZ to R35HZ), which only decreases in the following hours. In contrary to that, the reactance value increases.…”

Section: Discussionmentioning

confidence: 99%

“…This should be considered for the interpretation of blood gas values. It should be noted that there have been few blood-gas analysis measurements of newborn calves, bearing in mind that in the relevant publications, data collection does not continue until the third week of life [30, 43, 60–62]. …”

Section: Discussionmentioning

confidence: 99%

“…The question, whether a full ventilationof the lungs is reached within 12 hours p. n. for healthy, vital bovine neonates, has not yet been finally clarified [24–26]. Various research teams presume due to histological findings that the lung maturation in the alveoli stage still takes place in the first post uterine phase in neonatal ruminants [16, 27–30]. Serial radiographic-sonographic studies in vivo on native vital, healthy bovine individuals could not reveal whether 12 hours after birth the pulmonary tissue is fully ventilated [31].…”

Section: Introductionmentioning

confidence: 99%

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Computer Tomographic Illustration of the Development of the Pulmonary Function in Bovine Neonates until the Twenty-First Day Postnatum

Linke

Bostedt

Richter

2013

Veterinary Medicine International

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The aim of this study was to analyze the development of the lung in newborn calves. The sample consisted of 28 Holstein Friesians calves which were examined clinically, and their chest segment was measured with computed tomography. The tests were performed on the first, sixth, and twelfth hours of life and after the first, second, and third weeks. Also, blood gases and blood counts were determined. Besides Kolmogorov-Smirnov tests, analyses of variance, t-tests (on a significance level of P < 0.05), and correlation analyses were used. The most significant changes occurred between birth and the first hour. However, there were significant differences in the gas filling between cranial and caudal and between dorsal and ventral parenchyma segments. This difference remained over the entire study period. At the end of the first week between 85 and 93% were involved in gas exchange. Only after the completion of the second week of life, the air supply was achieved throughout the whole lung. The pO2, pCO2, and pH values confirmed this. This study shows that a healthy bovine neonate needs about 2 weeks before all lung units are integrated into the gas exchange. This explains why calves in unfavorable environments often suffer from pulmonary affections.

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