Mechanical Heart Valve Performance in a Pulsatile Pediatric Ventricular Assist Device

Zapanta, Conrad M.; Dourte, Leann M.; Doxtater, Bradley; Lukic, Branka; Weiss, Jason

doi:10.1097/01.mat.0000247959.37562.0a

Cited by 3 publications

(1 citation statement)

References 16 publications

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“…As stated in Ref. [36] bileaflet valves have a tendency to regurgitate more when positioned at 90°. This was observed in this work, nonetheless, no tendency of increasing regurgitation was found in‐between angles (15° to 60°).…”

Section: Discussionmentioning

confidence: 87%

Effect of the bileaflet inlet valve angle on the flow of a pediatric ventricular assist device: Experimental analysis

et al. 2022

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Background: Mechanical heart valves (MHV) and its fluid dynamics inside a pulsatile pediatric ventricular assist device (PVAD) can be associated with blood degradation. In this article, flow structures are analyzed and compared by an experimental investigation on the effect of bileaflet MHV positioned at varying angles in the inlet port orifice of a PVAD.Methods: Time-resolved particle image velocimetry was applied to characterize the internal flow of the device. St Jude Medical bileaftlet valves were used on the inlet orifice and positioned at 0°, 15°, 30°, 45°, 60°, and 90° in relation to the centerline of the device. Three planes with bidimensional velocity magnitude fields were considered in the analysis with visualization of diastolic jets, device wall washing patterns and flow circulation during emptying or systole of the pump. Also, the washing vortex area, and vertical velocity probabilities of regurgitant flows in the inlet valve were evaluated. Results:The results show that a variation in the angle of the MHV at the inlet port produced distinct velocities, fluid structures, and regurgitant flow probabilities within the device. MHV positioned at an angle of 0° generated the strongest inlet jet, larger vortex area during filling, more prominent outgoing flow, and less regurgitation compared to the angles studied. The presence of unfavorable fluid structures, such as small vortices, and/or sudden flow structure interruption, and/or regurgitation, were identified at 45° and 90° angles. Conclusions:The 0° inlet angle had better outcomes than other angles due to its consistency in the multiple parameters analyzed.

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Section: Discussionmentioning

confidence: 87%

Effect of the bileaflet inlet valve angle on the flow of a pediatric ventricular assist device: Experimental analysis

et al. 2022

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International Conference on Pediatric Mechanical Circulatory Support Systems and Pediatric Cardiopulmonary Perfusion

Ündar¹

2008

ASAIO Journal

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The overall objective of this unique meeting is to bring together internationally known clinicians, bioengineers, and basic scientists involved in the research of pediatric mechanical cardiac support systems and pediatric cardiopulmonary bypass procedures. The primary focus is to explicitly describe the problems with current pediatric mechanical circulatory support systems, methods, and techniques during acute and chronic support. The organizers of these continuing events believe that, in bringing together respected international scholars from 27 different countries, there has been a significant global impact made on the treatment of pediatric cardiac patients during the past three years alone. Over 800 participants from many countries, including Argentina, Australia, Austria, Belgium, Brazil, Canada, China, Finland, France, Germany, Greece, Ireland, Italy, Japan, Kuwait, Netherlands, New Zealand, Poland, South Korea, Saudi Arabia, Scotland, Spain, Switzerland, Taiwan, Turkey, the United Kingdom, and the United States, have participated in the 2005, 2006, and 2007 events.To date, this International Conference on Pediatric Mechanical Circulatory Support Systems and Pediatric Cardiopulmonary Perfusion is the only conference solely dedicated to pediatric cardiac devices during acute and chronic mechanical circulatory support. There is no other national or international conference to precisely define the problems with pediatric cardiac patients, and to suggest solutions with new methodologies and devices for pediatric patients, specifically neonates and infants. The objectives of this editorial are to review the outcomes of these three events and share future directions. Formal Conference EvaluationsParticipants at the last three events were requested to evaluate all scientific and social programs comprising the 3 day conferences. The survey questions covered not only educational objectives of the event, but also conference administration, facilities, and personal (717) 531-0355; e-mail: aundar@psu.edu. Publisher's Disclaimer: DISCLAIMER Articles made available through LWW's Publish Ahead of Print service may contain statements, opinions, and information that have errors in facts, figures, or interpretation. In order to disseminate this information as quickly as possible, we are posting articles without copyediting or proofing for publication. Please consult a qualified professional for medical or scientific advice. Accordingly, the publisher, the editors and authors and their respective employees accept no liability for the consequences of any such inaccurate or misleading data, opinion or statement. expectations. In addition, Invited and Key Note Lecturers were evaluated in terms of teaching effectiveness, knowledge of the subject, quality of handouts, teaching strategies, and commercial bias. The ratings in all categories were remarkably high. A majority of the participants clearly stated that they learned something new which they would utilize in the coming year and share with others in their hospitals or insti...

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A Novel Approach to the In Vitro Hydrodynamic Study of the Aortic Valve: Mock Loop Development and Test

Vismara¹,

Fiore²,

Mangini³

et al. 2010

ASAIO Journal

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The aortic root functional unit (ARFU) is a complex structure whose functions are strictly dependent on the biomechanical interaction among each of its anatomically defined elements. The classical approach to the in vitro study of aortic hydrodynamics does not take this complexity into account. We propose a novel methodology based on the possibility to house whole natural ARFU samples in a purposely designed pulsatile mock loop, allowing for aortic surgery simulation. To point out the usability and potentialities of the device, the mock loop was tested with untreated porcine ARFU samples and with one ARFU prosthesized with a state-of-the-art bioprosthesis. The sample holder design was proved to allow the clinician to house and treat the ARFU sample in the mock loop with easiness and repeatability. The valve leakage with the prosthesized ARFU was comparable with literature data, and Effective orifice areas were consistent with the constructor's data. In contrast, the recorded pressure drops exceeded the data from the manufacturer and were quite aligned with in vivo postop echo-Doppler data acquired in implant recipients. This result suggests that our apparatus and methodology provide a way to investigate aortic hydrodynamic phenomena that resemble in a close way to those taking place in the final recipients' circulation.

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Mechanical Heart Valve Performance in a Pulsatile Pediatric Ventricular Assist Device

Cited by 3 publications

References 16 publications

Effect of the bileaflet inlet valve angle on the flow of a pediatric ventricular assist device: Experimental analysis

Effect of the bileaflet inlet valve angle on the flow of a pediatric ventricular assist device: Experimental analysis

International Conference on Pediatric Mechanical Circulatory Support Systems and Pediatric Cardiopulmonary Perfusion

A Novel Approach to the In Vitro Hydrodynamic Study of the Aortic Valve: Mock Loop Development and Test

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