Mechanical and tribological properties of a novel hydrogel composite reinforced by three-dimensional woven textiles as a functional synthetic cartilage

Arjmandi, Mohammadreza; Ramezani, Maziar; Bolle, Tim; Köppe, Gesine; Gries, Thomas; Neitzert, Thomas

doi:10.1016/j.compositesa.2018.09.018

Cited by 24 publications

(14 citation statements)

References 44 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The spacer fabric restricts the swelling and thereby, importantly, preserves the FCD, leading to an osmotic pressure which gives the HydroSpacers their load-bearing properties [ 47 ]. This observation is in line with the outcomes of numerical data showing that the load-bearing capacity of cartilage is highly dependent on the osmotic pressure [ 38 ], which is different from other reinforcement strategies using woven scaffolds, where the stiffness of the construct was dependent on the porosity and the pore size instead of the hydrogel used, as demonstrated in this study [ 67 , 69 , 70 ].…”

Section: Resultssupporting

confidence: 89%

“…The addition of the spacer fabric to the hydrogel lead to a faster and increased relaxation of the construct, which was similarly observed in the native cartilage. This time-dependent behavior was also observed when a polyacrylamide-alginate hydrogel was introduced into a woven textile [ 67 ]. The effect of the addition of the spacer fabric on the time-dependent properties was already apparent at day 0.…”

Section: Resultsmentioning

confidence: 63%

See 1 more Smart Citation

Creating a Functional Biomimetic Cartilage Implant Using Hydrogels Based on Methacrylated Chondroitin Sulfate and Hyaluronic Acid

Schuiringa

Mihajlovic

Donkelaar

et al. 2022

Gels

View full text Add to dashboard Cite

The load-bearing function of articular cartilage tissue contrasts with the poor load-bearing capacity of most soft hydrogels used for its regeneration. The present study explores whether a hydrogel based on the methacrylated natural polymers chondroitin sulfate (CSMA) and hyaluronic acid (HAMA), injected into warp-knitted spacer fabrics, could be used to create a biomimetic construct with cartilage-like mechanical properties. The swelling ratio of the combined CSMA/HAMA hydrogels in the first 20 days was higher for hydrogels with a higher CSMA concentration, and these hydrogels also degraded quicker, whereas those with a 1.33 wt% of HAMA were stable for more than 120 days. When confined by a polyamide 6 (PA6) spacer fabric, the volumetric swelling of the combined CSMA/HAMA gels (10 wt%, 6.5 × CSMA:HAMA ratio) was reduced by ~53%. Both the apparent peak and the equilibrium modulus significantly increased in the PA6-restricted constructs compared to the free-swelling hydrogels after 28 days of swelling, and no significant differences in the moduli and time constant compared to native bovine cartilage were observed. Moreover, the cell viability in the CSMA/HAMA PA6 constructs was comparable to that in gelatin–methacrylamide (GelMA) PA6 constructs at one day after polymerization. These results suggest that using a HydroSpacer construct with an extracellular matrix (ECM)-like biopolymer-based hydrogel is a promising approach for mimicking the load-bearing properties of native cartilage.

show abstract

Section: Resultssupporting

confidence: 89%

Section: Resultsmentioning

confidence: 63%

Creating a Functional Biomimetic Cartilage Implant Using Hydrogels Based on Methacrylated Chondroitin Sulfate and Hyaluronic Acid

Schuiringa

Mihajlovic

Donkelaar

et al. 2022

Gels

View full text Add to dashboard Cite

show abstract

“…Arjmandi et al. [15] studied mechanical and tribological properties of three-dimensional woven fabric-reinforced hydrogel composite from acrylamide and sodium alginate for a potential cartilage replacement material. N , N ′-methylene bis-acrylamide as the crosslinker of acrylamide and calcium chloride as the crosslinker of sodium alginate were used in the study.…”

Section: Introductionmentioning

confidence: 99%

One-step preparation of woven fabric-reinforced hydrogel composite

Koc

Aykut

Eren

2019

Journal of Industrial Textiles

View full text Add to dashboard Cite

Cotton-woven fabric-reinforced polyvinyl alcohol-based hydrogel composite was produced by constructing cotton as warp and polyvinyl alcohol/cotton hybrid and polyvinyl alcohol yarns as weft yarns in the fabric structure. As-prepared polyvinyl alcohol/cotton fabrics were treated with different concentrations of aqueous borax and glutaraldehyde crosslinking solutions. Polyvinyl alcohol molecules were transformed to crosslinked gel structure after the treatments. Since cotton yarns kept their yarn structure in the fabrics, woven fabric-reinforced hydrogel composites were obtained. Chemical analysis to investigate crosslinking was conducted by attenuated total reflection–Fourier transform infrared spectroscopy spectra analysis, and the results revealed that a proper crosslinking of polyvinyl alcohol molecules in polyvinyl alcohol yarns occurred by using both borax and glutaraldehyde as crosslinkers. Thermal stabilities of the samples were observed via thermogravimetric analysis measurements. Even though borax crosslinking increased the thermal stability, glutaraldehyde crosslinking did not have a significant effect on the thermal stability of hydrogel composite. Crystalline microstructural analysis was carried out with X-ray diffraction measurement. Tensile properties of the samples by focusing on the crosslinker ratio and water contents in the hydrogel composites were performed. The results revealed that tensile properties of hydrogel composite tremendously increased with fabric reinforcement. Also, breaking force gradually increased when the hydrogel composite structure released the water from its structure at both borax and glutaraldehyde samples. Since the produced fabric-reinforced hydrogel composites have high strength, they are promising candidates as hygroscopic materials for planting and erosion control at inclined terrains.

show abstract

“…5,6 For younger patients suffering from focal cartilage loss or osteoarthritis, provisional solutions that preserve healthy tissue areas, improve joint function, and delay surgical intervention have been suggested. 5–7…”

Section: Introductionmentioning

confidence: 99%

High-performance bilayer composites for the replacement of osteochondral defects

Oliveira

Silva

Figueiredo³

et al. 2022

Biomater. Sci.

View full text Add to dashboard Cite

show abstract

Mechanical and tribological properties of a novel hydrogel composite reinforced by three-dimensional woven textiles as a functional synthetic cartilage

Cited by 24 publications

References 44 publications

Creating a Functional Biomimetic Cartilage Implant Using Hydrogels Based on Methacrylated Chondroitin Sulfate and Hyaluronic Acid

Creating a Functional Biomimetic Cartilage Implant Using Hydrogels Based on Methacrylated Chondroitin Sulfate and Hyaluronic Acid

One-step preparation of woven fabric-reinforced hydrogel composite

High-performance bilayer composites for the replacement of osteochondral defects

Contact Info

Product

Resources

About