Journal of Chromatography A 2012 DOI: 10.1016/j.chroma.2011.12.065 View full text
Fabrice Gritti, Georges Guiochon

Abstract: The mass transfer mechanisms in silica monolithic columns of the second generation were investigated, using four research samples (two 2.3 mm × 50 mm and two 3.2 mm × 50 mm silica rods) provided by their manufacturer. The heights equivalent to a theoretical plate (HETP) of these columns were measured in a range of mobile phase velocities, following a meticulous experimental protocol. The coefficients of the van Deemter equation (longitudinal diffusion term B/u(S), skeleton/eluent mass transfer resistance term …

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