Measurement of sternal curvature angle on patients with pectus excavatum

Lee, Cory; Zavala-Garcia, Abraham; Teekappanavar, Neha; Lee, Catherine; Idowu, Olajire; Kim, Sung Hoon

doi:10.1007/s00383-016-3996-9

Cited by 2 publications

(3 citation statements)

References 6 publications

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“…Recent studies hypothesize that the inward deformation of the anterior thoracic in PE may happen due to the growth disturbance of the sternum [ 115 , 116 , 117 ]. Both Haje et al (1999, 2021) and Lee at al.…”

Section: The Anatomopathological and Biomechanical Perspectivesmentioning

confidence: 99%

“…Both Haje et al (1999, 2021) and Lee at al. (2017), assessed the shape of the sternum in patients with chest wall deformities versus normal [ 115 , 116 , 117 ]. They observed that the sternum in patients with PE reveal abnormal shape, posterior curvature, torsion, and sometimes relatively sudden angulation [ 117 ].…”

Section: The Anatomopathological and Biomechanical Perspectivesmentioning

confidence: 99%

“…They observed that the sternum in patients with PE reveal abnormal shape, posterior curvature, torsion, and sometimes relatively sudden angulation [ 117 ]. Based on these findings, they concluded that the developmental disturbances of the sternum might play a role in the etiopathogenesis of chest wall deformities, including PE [ 115 , 116 , 117 ]. They and advocated for further histologic studies of the sternal growth plates [ 117 ].…”

Section: The Anatomopathological and Biomechanical Perspectivesmentioning

confidence: 99%

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Current Concepts in the Etiology and Pathogenesis of Pectus Excavatum in Humans—A Systematic Review

David

2022

JCM

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Pectus excavatum (PE) is the most common deformity of the chest wall and is characterized by the posterior depression of the sternum and the lower costal cartilages. To date, the etiology of PE in humans remains enigmatic. Several etiologic hypotheses have been proposed over the past two centuries. However, most of them have been scientifically dismissed and now have only historic value. In this systematic review, we assess scientific publications of the past two centuries addressing the issue of the origin of PE in humans. We present and discuss the histologic, genetic, biomechanical, and experimental scientific achievements that contributed to the clarification of its etiology and pathogenesis. With no clear consensus over the exact mechanism, most recent studies agree that the primordial defect leading the deformation of the anterior chest wall in PE is related to the costal hyaline cartilage structure and function. Further studies on this subject must be carried out. Genetic studies seem to be the most promising way to understand the exact mechanism of PE’s origin and pathogenesis.

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Section: The Anatomopathological and Biomechanical Perspectivesmentioning

confidence: 99%