Measurement of intrarenal blood flow. I. Analysis of microsphere method

Mechanism of the Redistribution of Renal Cortical Blood Flow during Hemorrhagic Hypotension in the Dog

“…This method has been extensively evaluated in this (12) and other laboratories (11,14,15) three studies in the dog these authors noted a greater flow rate in the superficial cortex with the microsphere method than with the AGBM technique, this same group also found a similar alteration in the distribution of cortical flow during saline diuresis in the dog with the two methods (18). Although alterations in flow velocity may have some rheologic effect on the microspheres, the data obtained to date would suggest that the radioactive microsphere method is a valid index of the distributional changes which occur in a given experimental model.…”

Postnatal Changes in Renal Glomerular Blood Flow Distribution in Puppies

“…Thus, this method provides more information than examining only the outer two-thirds and the inner one-third of the cortex, as done in all previously published studies in puppies (19,28,38). The separation of the cortex into more than four zones, as has been done in adult dogs (39,40), is not applicable to the cortex of the newborn which is only 2-3 mm thick.…”

Effect of variation in dietary NaCl intake on the intrarenal distribution of plasma flow in the rat

“…These studies were performed in human subjects using inert gas washout techniques. Perhaps species difference as well as differences in analytic techniques (19) account for the disparate results.…”