Measurement of Hydroxyl Radical-Generated Methane Sulfinic Acid by High-Performance Liquid Chromatography and Electrochemical Detection

Palladium catalyzed reductive homocoupling reactions of aromatic halides in dimethyl sulfoxide (DMSO) solution

“…But the binding energy peak for the curve B just like that for the curve C shifts to around 336 eV, a characteristic binding energy for the Pd 0 metal [32,33], indicating that the oxidative Pd 2+ complex has been reduced into the Pd 0 active species by solvent DMSO, and the presence of a suitable base (CsF) is essential for the reduction even at the elevated temperature. DMSO solvent has been reported as a reducing reagent in other reaction systems [34][35][36]. For example by persulfate ion, DMSO could be oxidized into the corresponding radical cation, which could be used as a polymerization catalyst for acrylonitrile [36].…”

Determination of hydroxyl radicals in advanced oxidation processes with dimethyl sulfoxide trapping and liquid chromatography

“…Thirdly, it is nontoxic at relatively high concentrations, which makes it suitable to determine • OH in some AOPs involving microorganism [18,19]. Fourthly, it is highly reactive with the hydroxyl radicals (k = 4.5 ∼ 7.1 × 10 9 mol L −1 s −1 ) forming methanesulfinic acid (MSA), methyl radicals and formaldehyde [20][21][22][23]:…”

“…In the past decades, methanesulfinic acid has been adopted for determination of hydroxyl radicals by spectphotometric method [20,21] and HPLC [22,23]. However, recent study [24,25] indicates that methanesulfinic acid is only an intermediate product, which also reacted rapidly with hydroxyl radicals leading to methanesulfonic acid and sulfate formation (k = 6.2 ∼ 12 × 10 9 mol L −1 s −1 ).…”

Is Measuring OH. Radical Scavenging a Reasonable Measurement of Antioxidant Properties?

“…The formation of methane25–27 and/or methane‐sulfinic acid28,29 in the presence of (CH 3 ) 2 SO in vitro and even in vivo is used as evidence of the presence of hydroxyl radicals in the system. This is based on the known reaction of hydroxyl radicals with (CH 3 ) 2 SO, reactions (32)–(33) followed by reaction (34) 30…”

“…Thus the formation of CH 4 25–27 and/or (CH 3 )S(O)OH28,29 is considered as proof for the existence of hydroxyl radicals in the system. Observation of the methyl adduct to a spin trap in a system containing (CH 3 ) 2 SO is also considered as a proof to the formation of hydroxyl radicals in the system 31.…”