Maturation of an Idea: A Historical Perspective on the Association of Psoriasis With the Metabolic Syndrome and Cardiovascular Disease

The association of metabolic syndrome and psoriasis: a population‐ and hospital‐based cross‐sectional study

“…This finding is in concordance with the recent meta-analysis, which implied significance for hospital-based PS subjects only. 3 Obesity was identified as a possible confounder, partlybut not exclusively explaining the associations. Inflammation was not found to be a confounder.…”

A Population- and Hospital-based Cross-sectional Study of Renal Function in Hidradenitis Suppurativa

“…Iben M. MILLER 1 Thus, yielding a statistically significant age-, sex-, smoke-, BMI-, hypertension-and diabetes-adjusted MD of 6.81 ml/min/1.73 m 2 ((95% CI 1.27-12.35) (p = 0.0119) for the hospital HS group vs. the non-HS group, and a statistically non-significant age-, sex-, smoke-, BMI-, hypertension-and diabetes-adjusted MD of 1.53 ml/ min/1.73 m 2 (95% CI -0.35-3.41) (p = 0.1322) for the population HS group vs. non-HS group (Fig. 1, Tables SII and SIII 1 ).…”

“…During the last decade evidence that chronic inflammatory skin diseases may be linked to systemic disorders has accumulated. For example, psoriasis has been linked to metabolic syndrome and cardiovascular disease, and recently also to renal dysfunction (1)(2)(3)(4).…”

“…, Nicholas CARLSON 2 , Ulla B. MOGENSEN3 , Christina ELLERVIK4 and Gregor B. E. JEMEC1 The age-, sex-and smoke-adjusted analysis revealed a mean eGFR of 94.63 ml/min/1.73 m 2 (95% CI 89.99-99.27) for the hospital HS group, 88.00 ml/min/1.73 m 2 (95% CI 86.72-89.29) for the population HS group, and 88.41 ml/min/1.73 m 2 (95% CI 88.10-88.71) for the population non-HS group. Thus, yielding a statistically significant age-, sex-and smoke-adjusted MD of 6.= 0.7866) for the population HS group vs. the non-HS group(Tables SII and SIII 1 ).The age-, sex-, smoke-, BMI-, hypertension-and diabetes-adjusted analysis revealed a mean eGFR of 95.53 ml/min/1.73 m 2 (95% CI 90.66-100.40) for the hospital HS group, 90.25 ml/min/1.73 m 2 (95% CI 88.55-91.96) for the population HS group, and 88.72 ml/min/1.73 m 2 (95% CI 88.10-89.34) for the population non-HS group.…”

Quantifying cardiovascular disease risk factors in patients with psoriasis: a meta-analysis

“…an atherogenic lipid profile, hypertension, obesity and diabetes. The possible associations between cardiovascular risk factors and psoriasis have been investigated in numerous articles over the past 100 years, and results have been variable; however, a recent comprehensive meta‐analysis using categorical outcomes confirmed that the association is statistically significant . These indications are based on categorical outcome, e.g.…”