Maturation of an Idea: A Historical Perspective on the Association of Psoriasis With the Metabolic Syndrome and Cardiovascular Disease

The association of metabolic syndrome and psoriasis: a population‐ and hospital‐based cross‐sectional study

“…In aggregate, these data therefore imply that the comorbidities of PS are clinically significant in hospital PS subjects, and for some MetS parameters also population PS subjects. This finding is in concordance with the recent meta‐analysis, which implied significance for hospital‐based PS subjects only …”

“…This finding is in concordance with the recent meta-analysis, which implied significance for hospital-based PS subjects only. 3 Obesity was identified as a possible confounder, partlybut not exclusively explaining the associations. Inflammation was not found to be a confounder.…”

A Population- and Hospital-based Cross-sectional Study of Renal Function in Hidradenitis Suppurativa

“…Iben M. MILLER 1 Thus, yielding a statistically significant age-, sex-, smoke-, BMI-, hypertension-and diabetes-adjusted MD of 6.81 ml/min/1.73 m 2 ((95% CI 1.27-12.35) (p = 0.0119) for the hospital HS group vs. the non-HS group, and a statistically non-significant age-, sex-, smoke-, BMI-, hypertension-and diabetes-adjusted MD of 1.53 ml/ min/1.73 m 2 (95% CI -0.35-3.41) (p = 0.1322) for the population HS group vs. non-HS group (Fig. 1, Tables SII and SIII 1 ).…”

“…During the last decade evidence that chronic inflammatory skin diseases may be linked to systemic disorders has accumulated. For example, psoriasis has been linked to metabolic syndrome and cardiovascular disease, and recently also to renal dysfunction (1)(2)(3)(4).…”

“…, Nicholas CARLSON 2 , Ulla B. MOGENSEN3 , Christina ELLERVIK4 and Gregor B. E. JEMEC1 The age-, sex-and smoke-adjusted analysis revealed a mean eGFR of 94.63 ml/min/1.73 m 2 (95% CI 89.99-99.27) for the hospital HS group, 88.00 ml/min/1.73 m 2 (95% CI 86.72-89.29) for the population HS group, and 88.41 ml/min/1.73 m 2 (95% CI 88.10-88.71) for the population non-HS group. Thus, yielding a statistically significant age-, sex-and smoke-adjusted MD of 6.= 0.7866) for the population HS group vs. the non-HS group(Tables SII and SIII 1 ).The age-, sex-, smoke-, BMI-, hypertension-and diabetes-adjusted analysis revealed a mean eGFR of 95.53 ml/min/1.73 m 2 (95% CI 90.66-100.40) for the hospital HS group, 90.25 ml/min/1.73 m 2 (95% CI 88.55-91.96) for the population HS group, and 88.72 ml/min/1.73 m 2 (95% CI 88.10-89.34) for the population non-HS group.…”