Maternal Supplementation With Natural or Synthetic Vitamin E and Its Levels in Human Colostrum

Clemente, Heleni Aires; Ramalho, Heryka Myrna Maia; Lima, Mayara Santa Rosa; Grilo, Evellyn Câmara; Dimenstein, Roberto

doi:10.1097/mpg.0000000000000635

Cited by 30 publications

(51 citation statements)

References 40 publications

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“…Another important issue would be to encourage the nutritional care of the mother-child dyad in the follow-up of lactation to address a possible deficiency of this vitamin, either by encouraging the consumption of their food source, or by possible maternal supplementation with this vitamin, since there is evidence that maternal supplementation in the postpartum period may reflect an increase in the concentration of alpha-tocopherol in breast milk 27 . There is no guidance to supplement the child with vitamin E in the wake of lactation, because their disability is poorly explored in the literature.…”

Section: Discussionmentioning

confidence: 99%

Vitamina E No Leite Humano E Sua Relação Com O Requerimento Nutricional Do Recém-Nascido a Termo

Silva

Ribeiro

Melo

et al. 2017

Rev. paul. pediatr.

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Objectives: To determine the alpha-tocopherol concentration in breast milk at different periods of lactation and to estimate the possible supply of vitamin E to the infant.Methods: A longitudinal observational study was carried out with 100 mothers at University Hospital Ana Bezerra (HUAB), at Universidade Federal do Rio Grande do Norte, in Santa Cruz (RN), Northeast Brazil. Samples of colostrum (n=100), transitional milk (n=77), and mature milk (n=63) were collected. Alpha-tocopherol was analyzed by high-performance liquid chromatography. Vitamin supply to the newborn was estimated by comparing the nutritional requirement of vitamin E (4 mg/day) with the potential daily intake of milk.Results: The mean alpha-tocopherol concentration found in colostrum, transitional, and mature milk was 40.5±15.0 µmol/L, 13.9±5.2 µmol/L, and 8.0±3.8 µmol/L, respectively (p<0.001). The possible effect of these milks offered to the infant 6.2 mg/day of vitamin E in colostrum, 4.7 mg/day in transitional milk, and 2.7 mg/day in mature milk (p<0.0001), shows that only the mature milk did not guarantee the recommended quantity of this vitamin.Conclusions: Alpha-tocopherol levels in human milk decrease through the progression of lactation, and the possible intake of colostrum and transitional milk met the nutritional requirement of the infant. Mature milk may provide smaller amounts of vitamin E. Thus, it is important to study the factors that are associated with such low levels.

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Section: Discussionmentioning

confidence: 99%

Vitamina E No Leite Humano E Sua Relação Com O Requerimento Nutricional Do Recém-Nascido a Termo

Silva

Ribeiro

Melo

et al. 2017

Rev. paul. pediatr.

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“…В ряде клинических исследований дока-зано, что синтетические витамины хорошо усваиваются человеком [15,28]. В последние годы в специально спланированных исследованиях получены новые убе-дительные подтверждения этому [29][30][31]. Наконец, при оценке биологической доступности витамина из пищево-го продукта за 100% принимают усвоение из препарата химически синтезированного вещества.…”

Section: заблуждения и предубеждения в отношении витаминовunclassified

Enriched Milk Drinks for Vitamin Deficiency Correction in Toddlers and Preschoolers

Митрофановна¹

2017

Vopr. sovr. pediatr.

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Федеральный исследовательский центр питания, биотехнологии и безопасности пищи, Москва, Российская Федерация В рационе детей старше 1 года после перехода к питанию с общего стола отмечается недостаток витаминов D, B 12 , C, а также фолатов, кальция, йода, железа, цинка

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“…Синтетические витамины идентичны природным по струк-туре, биологической активности и хорошо усваиваются организмом. В последние годы этому получены новые убедительные подтверждения [23].…”

Section: заключениеunclassified

Micronutrients in Children’s Diets and Use of Vitamin/Mineral Complexes

Коденцова¹,

Громова²,

Макарова³

2015

Pediatr. farmakol.

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Optimal provision of children with micronutrients determines their normal growth, mental and physical development, as well as health in general. Even a sufficiently energy demand-adequate and calorie-excessive diet comprised of natural products for children does not provide a child's body with a whole range of micronutrients. Due to insufficient stay of a child in the sun and long stay indoors, endogenous vitamin D synthesis in skin induced by ultraviolet exposure does not fulfill a body's need in this vitamin. As vitamin deficiency is usually accompanied by mineral deficiency, it is reasonable to prescribe vitamin/mineral complexes (VMC). High prevalence of polyhypoavitaminosis substantiates the use of coformulated vitamin forms in children's diets. Simultaneous vitamin intake is more physiologically natural; combination of vitamins is more effective than separate or isolated prescription of each of them. Preventive doses, i. e. the doses close to the physiological vitamin need of a child's body ensure the diet's vitamin adequacy, reduce the risk of vitamin deficiency and its consequences. Effectiveness of VMC use has been confirmed both for treatment and prevention of allergic diseases in children. The main requirement to VMC for children is the full range of vitamins and minerals, the deficiency whereof is identified especially often, in the doses fulfilling needs of a growing child.АКТУАЛЬНОСТЬ Известно, что оптимальная обеспеченность вита-минами и эссенциальными макро-и микроэлемента-ми определяет нормальный рост детей, их умственное и физическое развитие, а также здоровье в целом.Для характеристики обеспеченности ребенка микро-нутриентами используют два связанных, но не идентич-ных понятия -потребность в витаминах и минераль-ных веществах и рекомендуемая норма потребления. Потребность человека в витаминах и минеральных

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Maternal Supplementation With Natural or Synthetic Vitamin E and Its Levels in Human Colostrum

Abstract: Supplementation with both forms of α-TOH increased vitamin E concentrations in colostrum; however, the natural form was more efficient in increasing the levels.

Cited by 30 publications

References 40 publications

Vitamina E No Leite Humano E Sua Relação Com O Requerimento Nutricional Do Recém-Nascido a Termo

Vitamina E No Leite Humano E Sua Relação Com O Requerimento Nutricional Do Recém-Nascido a Termo

Enriched Milk Drinks for Vitamin Deficiency Correction in Toddlers and Preschoolers

Micronutrients in Children’s Diets and Use of Vitamin/Mineral Complexes

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