Search citation statements

Order By: Relevance

Paper Sections

Select...
1
1
1

Citation Types

4
209
0
2

Year Published

1993
1993
2007
2007

Publication Types

Select...
8

Relationship

0
8

Authors

Journals

citations
Cited by 136 publications
(215 citation statements)
references
References 0 publications
4
209
0
2
Order By: Relevance
“…The gene encoding the binding protein for IGFII, Igf2r, which is expressed exclusively from the maternal chromosome (Barlow e= al. 1991) like H19, has a maternal-specific island of DNA methylation within the gene itself that is maintained during the genome-wide demethylation after fertilization (Stoger et al 1993). Thus imprinting may accommodate both male-and female-specific DNA methylation.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…The gene encoding the binding protein for IGFII, Igf2r, which is expressed exclusively from the maternal chromosome (Barlow e= al. 1991) like H19, has a maternal-specific island of DNA methylation within the gene itself that is maintained during the genome-wide demethylation after fertilization (Stoger et al 1993). Thus imprinting may accommodate both male-and female-specific DNA methylation.…”
Section: Discussionmentioning
confidence: 99%
“…Stoger et al (1993) localized a region in an intron of the Igf2r gene that is methylated on the expressed maternal allele. This region was also methylated in oocyte DNA but not in sperm DNA, a requirement for a candidate for the imprinting signal.…”
mentioning
confidence: 99%
“…Méthylation of this region is already present in the female gamete and remains unchanged during preimplantation develop ment and in the adult. Maternal méthylation of this region was proposed to represent the primary im printing signal for the mouse Ig f2 r gene (Stoger et al, 1993;Barlow, 1994).…”
Section: Cpg 1 Is Completely Unmethylated On Both Parental Igf2r Allementioning
confidence: 99%
“…The Air promoter is pre-emptively methylated during female gametogenesis and this is maintained on the maternal chromosome in diploid cells. Methylation of the Igf2r promoter is acquired on the paternal allele coincident with silencing in post-implantation embryos and is present in all tissues except brain, where the paternal Igf2r promoter is active (Stoger et al 1993;Hu et al 1999). The methylation mark on the maternal Air promoter constitutes the "imprint" for this gene cluster and the late acquisition of methylation on the paternal Igf2r promoter may act to maintain silencing in later developmental stages (Li et al 1993).…”
mentioning
confidence: 99%