“…Mathematical models have been proposed (DiStephano et aI., 1973) that integrate the combined effects of placental transfer of hormones and synthesis and secretion of new substances or metabolites by the placenta. Many review articles have analyzed the development of endocrine function in the human placenta and fetus (KIevit, 1966;Liu, 1966;Villee, 1969;Cleveland, 1970;Diczfaluzy, 1974). The specific endocrine secretions ofthe placenta are discussed in Chapter 12.…”