Maternal and Neonatal Outcomes of Critically Ill Pregnant and Puerperal Patients Diagnosed with COVID-19 Disease: Retrospective Comparative Study

Eman, Ali; Balaban, Onur; Kocayiğit, Havva; Süner, Kezban Özmen; Cırdı, Yaşar; Erdem, Alı Fuat

doi:10.3346/jkms.2021.36.e309

Cited by 11 publications

(10 citation statements)

References 25 publications

(31 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…We report 77.78 and 100% of deliveries by cesarean section in the two groups, respectively, and preterm delivery at 32 and 34 weeks for most patients in group 1, but for less than half of the patients in group 2. We report values closer to those of DiToro (85% cesarean prevalence) [51], Matar (76%) [52], and Eman (89.4%) [11]. Metz [53] also reported a 59.6% risk of cesarean birth and a 41.8% risk of preterm birth in severely critical pregnant COVID-19 patients, the latter in accordance with what we found in group 2.…”

Section: Discussionsupporting

confidence: 89%

“…In one study, Eman [11] reported an ICU mortality rate of 42.1%, representing all eight COVID-19 pregnant patients who were intubated and mechanically ventilated. Lokken [3] and Moieindarbary [12] reported only one patient admitted to the ICU, who subsequently died of respiratory failure after a prolonged ICU stay despite multiple COVID-19 therapeutics, which is a 100% mortality rate.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Brixia Score in Outcomes of Alpha versus Delta Variant of Infection in Pregnant Critical COVID-19 Patients

Covali

Socolov

Păvăleanu

et al. 2022

IJTM

View full text Add to dashboard Cite

Background: Critical COVID-19 patients account for 1.7 to 13% of all pregnant COVID-19 patients. Methods: Patients admitted to the COVID-19 intensive care unit of Elena Doamna Obstetrics and Gynecology University Hospital in Iasi between 1 January and 1 December 2021, with critical forms of the disease, were included and retrospectively studied. The patients’ age range was 25–44 years in the Alpha group (n = 12) and 27–52 years in the Delta group (n = 9). Results: Most critically ill pregnant COVID-19 patients in the Alpha group delivered when admitted to the intensive care unit, while less than half of those in the Delta group delivered when admitted; the rest were released home and continued their pregnancy normally. There was a significant difference regarding the number of patients released to home care and the number of days after admission when delivery occurred (p = 0.02 and 0.022, respectively). Conclusions: There was no significant difference in maternal and fetal outcomes between the two groups, except for the number of patients released to home care and the number of days after admission when delivery occurred. There was no correlation between any Brixia scores (H, L, A, E) and any maternal or fetal outcomes in both groups.

show abstract

Section: Discussionsupporting

confidence: 89%

Section: Introductionmentioning

confidence: 99%

Brixia Score in Outcomes of Alpha versus Delta Variant of Infection in Pregnant Critical COVID-19 Patients

Covali

Socolov

Păvăleanu

et al. 2022

IJTM

View full text Add to dashboard Cite

show abstract

“… 34 35 36 The selection of mode of delivery may have been based on the hospital infection control status and medical condition of pregnant women in addition to the previous history of cesarean delivery, failure of labor to progress, breech presentation, and premature rupture of membranes. 34 37 38 39 …”

Section: Discussionmentioning

confidence: 99%

Maternal and Neonatal Outcomes in Pregnant Women With Coronavirus Disease 2019 in Korea

Chung

Kim

et al. 2022

J Korean Med Sci

View full text Add to dashboard Cite

Background This study aimed to describe the maternal, obstetrical, and neonatal outcomes in pregnant women with coronavirus disease 2019 (COVID-19) and identify the predictors associated with the severity of COVID-19. Methods This multicenter observational study included consecutive pregnant women admitted because of COVID-19 confirmed using reverse transcriptase-polymerase chain reaction (RT-PCR) test at 15 hospitals in the Republic of Korea between January 2020 and December 2021. Results A total of 257 women with COVID-19 and 62 newborns were included in this study. Most of the patients developed this disease during the third trimester. Nine patients (7.4%) developed pregnancy-related complications. All pregnant women received inpatient treatment, of whom 9 (3.5%) required intensive care, but none of them died. The gestational age at COVID-19 diagnosis (odds ratio [OR], 1.096, 95% confidence interval [CI], 1.04–1.15) and parity (OR, 1.703, 95% CI, 1.13–2.57) were identified as significant risk factors of severe diseases. Among women who delivered, 78.5% underwent cesarean section. Preterm birth (38.5%), premature rupture of membranes (7.7%), and miscarriage (4.6%) occurred, but there was no stillbirth or neonatal death. The RT-PCR test of newborns’ amniotic fluid and umbilical cord blood samples was negative for severe acute respiratory syndrome coronavirus 2. Conclusion At the time of COVID-19 diagnosis, gestational age and parity of pregnant women were the risk factors of disease severity. Vertical transmission of COVID-19 was not observed, and maternal severity did not significantly affect the neonatal prognosis.

show abstract

“…Our univariate analysis of the respiratory interventions conducted during hospital stay indicated that both means of ventilation (mechanical and non-invasive) were significantly more used in the second group, while the mean length of hospital stay was significantly higher for those patients. A recent retrospective study assessed maternal and neonatal outcomes of 19 critically ill pregnant and puerperal patients in the clinical course of COVID-19, and the authors reported that 8 patients died, all of whom received mechanical ventilation, resulting in an ICU mortality rate of 42.1% [ 25 ]. Additionally, the authors discovered that the mean number of hospitalized days in ICU was significantly lower in patients who were discharged ( p = 0.037).…”

Section: Discussionmentioning

confidence: 99%

Risk Factors Associated with Severe Disease and Intensive Care Unit Admission of Pregnant Patients with COVID-19 Infection—A Retrospective Study

Adam

Vasilache

Socolov

et al. 2022

JCM

View full text Add to dashboard Cite

(1) Background: Pregnant patients with severe forms of coronavirus disease 2019 (COVID-19) can experience adverse pregnancy outcomes. The aim of this study was to retrospectively assess the risk factors associated with admission to the intensive care unit (ICU) of pregnant patients with COVID-19, as well as the pregnancy outcomes of these patients; (2) Methods: Medical records of 31 pregnant patients with COVID-19 admitted to three clinical hospitals from Romania, between October 2020 and November 2021 were examined. The patients were segregated into two groups depending on their clinical evolution: non-ICU admission (n = 19) or ICU admission (n = 12). Clinical and paraclinical findings were evaluated using univariate analysis, and the association of significant risk factors with maternal ICU admission was assessed using a multivariate analysis. Pregnancy outcomes of these patients were also recorded; (3) Results: Pulmonary disease, cough, dyspnea, leukocytosis, thrombocytosis, high serum values of transaminases, serum ferritin, and increased duration of hospital admission were identified as significant risk factors associated with maternal admission to the ICU. No significant differences regarding pregnancy outcomes were noted between the evaluated patients; (4) Conclusions: Specific risk factor identification in pregnant patients with severe forms of COVID-19 could improve the patient’s management.

show abstract

Maternal and Neonatal Outcomes of Critically Ill Pregnant and Puerperal Patients Diagnosed with COVID-19 Disease: Retrospective Comparative Study

Cited by 11 publications

References 25 publications

Brixia Score in Outcomes of Alpha versus Delta Variant of Infection in Pregnant Critical COVID-19 Patients

Brixia Score in Outcomes of Alpha versus Delta Variant of Infection in Pregnant Critical COVID-19 Patients

Maternal and Neonatal Outcomes in Pregnant Women With Coronavirus Disease 2019 in Korea

Risk Factors Associated with Severe Disease and Intensive Care Unit Admission of Pregnant Patients with COVID-19 Infection—A Retrospective Study

Contact Info

Product

Resources

About