volume 93, issue 0, P3-O-130 2020
DOI: 10.1254/jpssuppl.93.0_3-o-130
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Abstract: 【Background】 Maresin1 (MaR1), a lipid mediator biosynthesized from docosahexaenoic acid (DHA), has both anti-inflammatory and proresolving activities. Much attention has been paid to the functional regulation by MaR1 in inflammatory cells, but not in tissue component cells. Since inflammatory reactions are involved in cardiovascular diseases, we addressed the effects of MaR1 on cardiomyocytes. 【Methods & Results】 Neonatal rat cardiomyocytes (NRCMs) were cultured with MaR1 for 48 hours. Immunofluorescent micros…

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