Mapeamento de T1 na Insuficiência Cardíaca: Implicações Prognósticas

Moharem-Elgamal, Sarah

doi:10.36660/abc.20210205

Cited by 1 publication

(1 citation statement)

References 6 publications

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“…Native T1 mapping and enhanced T1 mapping, representing non-contrast and contrast-based T1 relaxation time measurements respectively, hold significant promise. In heart failure contexts, these techniques capture changes in the myocardium that may indicate early or evolving myocardial diseases, even before overt heart failure symptoms manifest ( 10 , 11 ). They provide a window into the cellular and extracellular matrix alterations that often precede clinical heart failure ( 12 ).…”

Section: Introductionmentioning

confidence: 99%

Distinguishing heart failure subtypes: the diagnostic power of different cardiac magnetic resonance imaging parameters

Hao,

Zhang,

Chen

et al. 2024

Front. Cardiovasc. Med.

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ObjectivesThe aim of this retrospective study was to explore the diagnostic potential of various cardiac parameters in differentiating between heart failure with preserved ejection fraction (HFpEF) and heart failure with mid-ranged and reduced ejection fraction (HFm + rEF), and to discern their relationship with normal cardiac function.MethodsThis research encompassed a comparative analysis of heart failure subtypes based on multiple indicators. Participants were categorized into HFm + rEF, HFpEF, and control groups. For each participant, we investigated indicators of left ventricular function (LVEDVi, LVESVi, and LVEF) and myocardial strain parameters (GLS, GCS, GRS). Additionally, quantitative tissue evaluation parameters including native T1, enhanced T1, and extracellular volume (ECV) were examined.For comprehensive diagnostic performance analysis, receiver operating characteristic (ROC) curve evaluations for each parameters were conducted.ResultsHFm + rEF patients exhibited elevated LVEDVi and LVESVi and decreased LVEF compared to both HFpEF and control groups. Myocardial strain revealed significant reductions in GLS, GCS, and GRS for HFm + rEF patients compared to the other groups. HFpEF patients showed strain reductions relative to the control group. In cardiac magnetic resonance imaging (CMR) evaluations, HFm + rEF patients demonstrated heightened native T1 times and ECV fractions. Native T1 was particularly effective in distinguishing HFpEF from healthy subjects.ConclusionNative T1, ECV, and myocardial strain parameters have substantial diagnostic value in identifying HFpEF. Among them, native T1 displayed superior diagnostic efficiency relative to ECV, offering critical insights into early-stage HFpEF. These findings can play a pivotal role in refining clinical management and treatment strategies for heart failure patients.

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Section: Introductionmentioning

confidence: 99%