Manifestações bucais em pacientes pediátricos infectados pelo HIV - uma revisão sistemática da literatura

Principais manifestações bucais em pacientes pediátricos HIV positivos e o efeito da terapia antirretroviral altamente ativa

“…Linear gingival erythema has also been described by some authors as a common oral manifestation in these patients 1,17 , besides also being considered as a unique feature of seropositive Crosssectional study…”

“…Cross-sectional and prospective studies have shown that pediatric HIV-infected patients will present some type of oral lesion in non-specific phases of their childhood, which will help to identify the correct diagnosis of the syndrome 1,2,17 and, consequently, to find the most suitableantiretroviral therapy treatment 4,9,11 . Chart 1.…”

“…Acquired Immunodeficiency Syndrome (AIDS) is a systemic disease caused by the Human Immunodeficiency Virus (HIV), which affects the individual's immune system and makes him/her more susceptible to other diseases of systemic origin, such as oral lesions 1 . First cases of AIDS were reported in the mid-1980s and its heterosexual transmission has grown over time, affecting a large number of women of childbearing age and capable of transmitting HIV virus to their children 2 .…”

“…Some oral manifestations in pediatric patients present a different prevalence of adult patients 9 . The prevalence of oral lesions is, on average, 63% 1,10 , ranging from 20% to 80% 11 . This variation may occur according to the region or country and type of treatment instituted, such as whether patients have access to more potent antiretroviral drugs 4 or not.…”

“…A wide variety of oral lesions in HIV-infected pediatric patients are reported in the literature, such as: candidiasis 8,[10][11][12] , gingivitis [12][13][14] , oral hairy leukoplakia 9,13 ,Kaposi's sarcoma 5,10,15 ,parotid enlargement 1,4,14,16 , herpes simplex 1,2 .This data also reveal divergence of information regarding which ones are the most frequent oral manifestations and how the antiretroviral therapies act on them. For this reason, this present study aims to identify the main oral lesions affecting pediatric patients with HIV, as well as the effects of ART and HAART on said lesions.…”