Mandible reconstruction using patient-specific pre-bent reconstruction plates: comparison of standard and transfer key methods

Wilde, Frank; Winter, Karsten; Kletsch, Katharina; Lorenz, K; Schramm, Alexander

doi:10.1007/s11548-014-1065-1

Cited by 52 publications

(45 citation statements)

References 23 publications

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“…Only 13 of the 48 studies mentioning reduced operation room time and supported this statement with actual numbers or statistics [ 3 , 39 , 44 , 72 , 74 , 78 , 81 , 84 , 99 , 107 , 117 , 119 , 120 ]. In 80 (89.89 %) of the publications, the printed part showed good accuracy, although this was only supported numerically in four studies [ 3 , 81 , 97 , 106 ]. Exposure to ionizing radiation was not mentioned in 77 (86.51 %) of the publications, and eight mentioned decreased exposures [ 3 , 59 – 61 , 74 , 79 , 101 , 107 ].…”

Section: Resultsmentioning

confidence: 97%

“…Surgical guides are the most popular medical application of 3D printing, with mentions in 137 of the 270 papers (50.74 %) [ 10 , 15 , 30 , 31 , 39 , 48 , 59 , 60 , 62 , 70 , 71 , 73 , 74 , 76 , 77 , 79 – 81 , 83 , 84 , 86 , 88 , 89 , 92 , 93 , 96 – 98 , 106 , 108 , 111 – 113 , 118 , 124 – 226 ]. Apart from orthopedics (guides for knee arthroplasties), 3D-printed surgical guides were also used in neurosurgery, dental surgery, spinal surgery, and maxillofacial surgery.…”

Section: Resultsmentioning

confidence: 99%

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3D-printing techniques in a medical setting: a systematic literature review

et al. 2016

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BackgroundThree-dimensional (3D) printing has numerous applications and has gained much interest in the medical world. The constantly improving quality of 3D-printing applications has contributed to their increased use on patients. This paper summarizes the literature on surgical 3D-printing applications used on patients, with a focus on reported clinical and economic outcomes.MethodsThree major literature databases were screened for case series (more than three cases described in the same study) and trials of surgical applications of 3D printing in humans.Results227 surgical papers were analyzed and summarized using an evidence table. The papers described the use of 3D printing for surgical guides, anatomical models, and custom implants. 3D printing is used in multiple surgical domains, such as orthopedics, maxillofacial surgery, cranial surgery, and spinal surgery. In general, the advantages of 3D-printed parts are said to include reduced surgical time, improved medical outcome, and decreased radiation exposure. The costs of printing and additional scans generally increase the overall cost of the procedure.Conclusion3D printing is well integrated in surgical practice and research. Applications vary from anatomical models mainly intended for surgical planning to surgical guides and implants. Our research suggests that there are several advantages to 3D-printed applications, but that further research is needed to determine whether the increased intervention costs can be balanced with the observable advantages of this new technology. There is a need for a formal cost–effectiveness analysis.Electronic supplementary materialThe online version of this article (doi:10.1186/s12938-016-0236-4) contains supplementary material, which is available to authorized users.

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Section: Resultsmentioning

confidence: 97%

Section: Resultsmentioning

confidence: 99%

3D-printing techniques in a medical setting: a systematic literature review

et al. 2016

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“… 115 To overcome the complications of conventional surgical plates, 3D technologies have facilitated the production of patient-specific pre-bent surgical plates. 63 , 116 - 119 Pre-bent selective laser 41 sintering (SLS) or milled titanium surgical plates with specific configurations, including the 3D architecture, width, thickness and screw holes, can be individualized for each patient using the patient’s original printed contours. 120 This type of plate has threaded screw holes with different angles and can tolerate a greater number of screws than a conventional plate and has a minimum distance between screws of 5.5 mm compared with the 8 mm of a conventional plate.…”

Section: Pre-bent Reconstruction Platesmentioning

confidence: 99%

Review of surgical resection and reconstruction in head and neck cancer

Alfouzan

2018

SMJ

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This review summarizes the development of head and neck cancer resection and reconstruction. The developments in the treatment of cancer patients are reflected in their surgical outcomes, in addition to functional and aesthetic improvements. New technologies, such as surgical simulation and planning, minimally invasive surgery, and microsurgery have been added to the field to improve surgical resection of the tumor and reconstruction. The field is still growing to optimize the management of head and neck cancer.

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“…Within last few years patient-customized craniofacial reconstructions become new standard in maxillofacial surgery. Patient specific 3D printed models can be used as a template for pre-shaping titanium mesh [1][2][3][4][5][6] or bone grafts [1,7,8] before implantation, to simulate osteotomies [1,9,10], to improve cancer resection techniques [11,12] and to better plan the surgery [7]. There are even possibilities to produce patient-specific implants using either subtractive [2,13] or additive methods like selective laser sintering [6,[14][15][16][17].…”

Section: Introductionmentioning

confidence: 99%

“…The most commonly 3D printing technique in maxillofacial surgery is stereolithography using liquid resin which is photopolymerised with a laser beam [6]. Models created with this material have already proven their usefulness in medicine [1,4,14,[17][18][19][20][21]. Three-dimensional objects manufactured in such 3D printer are durable enough to successfully undergo sterilization and serve as a template during the surgery.…”

Section: Introductionmentioning

confidence: 99%

Cytotoxicity of three-dimensional paper-based models from a three-dimensional paper-based printer

Kozakiewicz

Szymor

Olszewski³

2018

Nemesis

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Objective: Our study aimed to determine the possibility of using models created with a low-cost, paper based 3D printer in an operating room. Therefore influence of different methods of sterilization on models was tested and cytotoxicity of generated models was determined. Material and methods: 30 cuboids divided into three groups were used for verification of shape stability after sterilization. Each group was sterilized either with: Ethylene oxide in temperature 55˚C, Hydrogen peroxide gas plasma in temperature 60˚C or Gamma irradiation at 21˚C, 25kGy. Each cuboid was measured using calliper three times before and three times after sterilization. Results were analysed statistically in Statgraphics Plus. Statistical significance was determined as p< 0.05. Sixty cylinders divided into six groups were used for cytotoxicity tests. Three of those groups were covered before sterilization with 2-octyl-cyanoacrylate. Each group was sterilized with one of the previously described methods. Cytotoxicity was tested by Nanostructural and Molecular Biophysics Laboratory in Technopark Lodz using normal adult human dermal fibroblasts. Survival of cells was tested using spectrophotometry with XTT and was defined as ratio of absorbency of tested probe to absorbency of control probe. Calcein/Ethidium dyeing test was performed according to LIVE/DEAD Viability/Cytotoxicity Kit protocol. Observation was done under Olympus GX71 fluorescence microscope. Results: There was no statistically significant difference for established statistical significance p=0.05 in cuboids dimensions before and after sterilization regardless of sterilization method. In XTT analysis all samples showed higher cytotoxicity against normal, human, adult dermal fibroblast culture when compared to positive control. ANOVA statistical analysis confirmed that 2-octyl cyanoacrylate coating of paper model improved biological behaviour of the material. It decreased cytotoxicity of the model independently of sterilization method. In calcein/ethidium dyeing test due to the high fluorescence of the background caused by cylinders of analysed substance it was impossible to perform the exact analysis of the number of marked cells. Conclusions: Acquired results allow to conclude that Mcor Technology Matrix 300 3D paper-based models can be used in operating room only if covered with cyanoacrylate tissue adhesive. Nemesis relevance: We found no statistically significant difference in cuboids dimensions before and after sterilization regardless of sterilization method. Three-dimensional paper-based models present with high cytotoxicity without coating.

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Mandible reconstruction using patient-specific pre-bent reconstruction plates: comparison of standard and transfer key methods

Abstract: The TK-method was more accurate than the ST-method in a clinical trial. The TK-method was effective and accurate for mandible reconstruction using pre-bent fixation plates.

Cited by 52 publications

References 23 publications

3D-printing techniques in a medical setting: a systematic literature review

3D-printing techniques in a medical setting: a systematic literature review

Review of surgical resection and reconstruction in head and neck cancer

Cytotoxicity of three-dimensional paper-based models from a three-dimensional paper-based printer

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