Arch Dermatol
 2006
DOI: 10.1001/archderm.142.6.771
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Management of Merkel Cell Carcinoma

Murad Alam
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Cited by 16 publications

(3 citation statements)
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“…18 With a tripling in the incidence of MCC as discussed above, attention has been given to considering causes contributing to this rise including: improved clinical recognition, 19 the increasing elderly population and a higher number of patients in an immunosupressed state. 20 As defined by its high rate of recurrence, significant risk of metastatic disease and increasing incidence, MCC must be considered in the differential diagnosis of cutaneous malignancy. The diagnosis of MCC can be both clinically and histologically challenging.…”
Section: Discussionmentioning
confidence: 99%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…18 With a tripling in the incidence of MCC as discussed above, attention has been given to considering causes contributing to this rise including: improved clinical recognition, 19 the increasing elderly population and a higher number of patients in an immunosupressed state. 20 As defined by its high rate of recurrence, significant risk of metastatic disease and increasing incidence, MCC must be considered in the differential diagnosis of cutaneous malignancy. The diagnosis of MCC can be both clinically and histologically challenging.…”
Section: Discussionmentioning
confidence: 99%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…Histologically, this tumour is classified into trabecular, intermediate and small cell subtype . There is no evidence that the histological features correlate with the clinical outcome . Merkel cell carcinoma Stage I is defined as tumours ≤ 2 cm, Stage II as >2 cm, stage III as regional nodal disease, and stage IV as distant metastatic disease .…”
Section: Introductionmentioning
confidence: 99%
“…6,7 There is no evidence that the histological features correlate with the clinical outcome. 6,[8][9][10] Merkel cell carcinoma Stage I is defined as tumours ≤ 2 cm, Stage II as >2 cm, stage III as regional nodal disease, and stage IV as distant metastatic disease. 11 In general, lower stage disease is associated with better overall survival.…”
Section: Introductionmentioning
confidence: 99%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
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