Management of mechanical ventilation in patients with hospital-acquired pneumonia: A retrospective, observational study

Uvizl, Radovan; Herkel, Tomas; Langová, Kateřina; Jakubec, Petr

doi:10.5507/bp.2017.047

Cited by 2 publications

(2 citation statements)

References 32 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The clinical condition of severe pneumonia is critical, the fatality rate is high, and the curative effect and prognosis are poor; in the treatment of severe pneumonia with respiratory failure, mechanical ventilation is a common rescue method (Ocal et al, 2016;Uvizl et al, 2018). Mechanical ventilation can quickly improve the patient's lung ventilation function and relieve hypoxia and dyspnea, which is effective in the treatment of severe pneumonia with respiratory failure clinically (Tsuruta et al, 2014).…”

Section: Introductionmentioning

confidence: 99%

Untitled

2021

Pak. J. Pharm. Sci

View full text Add to dashboard Cite

To investigate the effects of dexmedetomidine combined with citrate sufentanil on the prognosis of patients with severe pneumonia and respiratory failure requiring mechanical ventilation. 70 patients with severe pneumonia complicated with respiratory failure who were treated with mechanical ventilation were selected and divided into the combined group and the control group. The control group underwent mechanical ventilation treatment and used dexmedetomidine for sedation and analgesia, while the combined group had sufentanil analgesia in addition to the treatment of the control group. Ramsay sedation score, visual analogue scale (VAS) and pulmonary function indicators were compared between the two groups before treatment, 24h after treatment, and after extubation. After 24h treatment and extubation, the blood oxygen saturation (SpO 2 ), oxygenation index (OI) and arterial oxygen partial pressure (PaO 2 ) in the combined group were higher than those in the control group; at the same time, the serum interleukin 6 (IL-6), tumor necrosis factor α (TNF-α), and malondialdehyde (MDA) levels were lower (P<0.05). Mortality during hospitalization of the combined group was lower than the control group (P<0.05). Dexmedetomidine combined with sufentanil citrate can effectively improve sedative and analgesic effects, stress response, pulmonary function and prognosis in patients with severe respiratory failure requiring mechanical ventilation.

show abstract

Section: Introductionmentioning

confidence: 99%

Untitled

2021

Pak. J. Pharm. Sci

View full text Add to dashboard Cite

show abstract

“…8 In line with the findings concerning the use of weaning protocols, only 31% to 44% of respondents have reported using sedation protocols [9][10] while adherence to pain management protocol has been hard to achieve and unacceptably high pain scores have been observed. 11 Late-onset hospital-acquired pneumonia 12 has been related to high peak inspiratory airway pressure (Ppeak), positive end-expiratory pressure (PEEP), and fraction of inspired oxygen. However, little is known about the relationship of these factors with intensive care unit (ICU)-acquired pneumonia and mortality.…”

Section: Introductionmentioning

confidence: 99%

Implementation of strategies to liberate patients from mechanical ventilation in a tertiary-level medical center

Jansson

Syrjälä

Ala‐Kokko

2019

American Journal of Infection Control

View full text Add to dashboard Cite

Background. Considerable discrepancies have been observed in the implementation of strategies to liberate patients from mechanical ventilation. The aim of this study was to describe critical care nurses' knowledge of and self-reported and documented adherence to lung-protective ventilation, daily sedation interruption, and daily assessment of readiness to extubate and evaluate how these practices differ between patients with and without ventilator-associated pneumonia and between survivors and nonsurvivors. Methods. The survey was conducted in a tertiary-level hospital in Finland from October 2014 to June 2015. Actual adherence was evaluated based on documentation of performed practices. Results. A total of 86 critical care nurses responded to the survey, and 85 patients were followed. The levels of knowledge of and self-reported adherence to low tidal ventilation were 84.5% and 90.2%, respectively, and the median tidal volume was at a target level in 74.4% of patients. Regarding daily sedation interruption, the level of knowledge was 85.7% and the level of self-reported adherence was 77.3% while documented adherence was 33.3%. The levels of knowledge and self-reported adherence regarding spontaneous breathing trial were 61.9% and 71.6%, respectively. Adherence to lungprotective ventilation, daily sedation interruption, and daily assessment of readiness to extubate did not differ between patients with (n=20) and without (n=65) ventilator-associated pneumonia and between survivors (n=55) and nonsurvivors (n=30). Conclusions. Lung-protective ventilation, including low-tidal ventilation and avoidance of high inspiratory plateau pressures, was well implemented and adhered to. The levels of knowledge and self-reported adherence versus documented adherence regarding daily sedation interruption and spontaneous breathing trial demonstrated insufficient implementation of local guidelines. There was no affect on the outcome.

show abstract

Management of mechanical ventilation in patients with hospital-acquired pneumonia: A retrospective, observational study

Cited by 2 publications

References 32 publications

Untitled

Untitled

Implementation of strategies to liberate patients from mechanical ventilation in a tertiary-level medical center

Contact Info

Product

Resources

About