2004
DOI: 10.1001/archderm.140.5.552
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Management of Lentigo Maligna and Lentigo Maligna Melanoma With Staged Excision

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Cited by 165 publications
(152 citation statements)
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References 30 publications
(51 reference statements)
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“…In our report, 6 of the 11 cases had clear margins after one stage with 2 mm strips excised outside of the initial 5 mm margin. The remaining five cases required 2-4 stages for clear margins and two cases required four stages, lending credence to the view that NIH-recommended margins may not be sufficient for LM and LMM [9,15,24].…”
Section: Discussionmentioning
confidence: 71%
See 2 more Smart Citations
“…In our report, 6 of the 11 cases had clear margins after one stage with 2 mm strips excised outside of the initial 5 mm margin. The remaining five cases required 2-4 stages for clear margins and two cases required four stages, lending credence to the view that NIH-recommended margins may not be sufficient for LM and LMM [9,15,24].…”
Section: Discussionmentioning
confidence: 71%
“…Out of 150 LM cases, only one short-term (<5 years) local recurrence has been reported using a similar staged excision technique [14]. In 62 lesions of LM and LMM, a 95% local control rate was reported at 5 years [24]. Mapped serial excision technique (MSE) is a related technique that has been used for periocular LM and LMM, with a reported 3% recurrence rate at 3 years [33].…”
Section: Discussionmentioning
confidence: 99%
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“…In contrast to surgical excision, MMS allows for the examination of 100% of the peripheral margins. Despite the advantages of MMS as a tissue-sparing procedure, controversy surrounds the use of frozen sections to identify malignant melanocytic cells (6). Pathological difficulties encountered include: vacuolated keratinocytes mimicking melanocytes, processing artifact, and dermal inflammatory cells that may obscure the melanocytes in frozen sections (7).…”
Section: Mohs Micrographic Surgerymentioning
confidence: 99%
“…For larger in situ cases and those of the lentigo maligna subtype, most CM surgeons aim for margins in the 5-to 10-mm range. 46,47 Palliation of symptoms is perhaps the surgeon's most important role in the local management of AM. Close to a quarter of patients reported in the series reviewed underwent surgery for palliative reasons.…”
Section: Managing the Tumor Sitementioning
confidence: 99%