2011
DOI: 10.1001/archoto.2011.56
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Management of Eustachian Tube Dysfunction With Nasal Steroid Spray

Abstract: These findings do not support the use of intranasal steroid sprays to treat the manifestations of eustachian tube dysfunction. Trial Registration clinicaltrials.gov Identifier: NCT00279916.

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Cited by 111 publications

(95 citation statements)
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“…11 Interestingly, randomized studies showed that NS alone may not outperform control for ETD, based on symptom scores and tympanometry. 19 In the current study, after pooling surgical conditions, NP staining with EDS delivery was significantly increased compared with conventional NS comparing average staining, which was further supported by the logistic regression model comparing the proportion of cadavers with significant staining. This supports the hypothesis that the EDS delivery mechanism may successfully lead to enhanced posterior penetration of intranasal medication.…”
Section: Discussion
supporting
confidence: 72%
How this paper cites the one you are viewing
“…11 Interestingly, randomized studies showed that NS alone may not outperform control for ETD, based on symptom scores and tympanometry. 19 In the current study, after pooling surgical conditions, NP staining with EDS delivery was significantly increased compared with conventional NS comparing average staining, which was further supported by the logistic regression model comparing the proportion of cadavers with significant staining. This supports the hypothesis that the EDS delivery mechanism may successfully lead to enhanced posterior penetration of intranasal medication.…”
Section: Discussion
supporting
confidence: 72%
How this paper cites the one you are viewing
“…However, conservative therapy typically has no long-term effect on chronic ET dysfunction, and thus, it is not routinely recommended. 12,13 Our results showed that this condition could be successfully treated with BET. Thus, we recommend offering BET to adult patients that only have symptoms of ET dysfunction because good long-term results can be expected.…”
Section: Discussion
mentioning
confidence: 59%
How this paper cites the one you are viewing
“…A sample size of 243 evaluable patients (162 in the investigational arm and 81 in the control arm) was estimated to provide 80% power to detect a difference between 45.0% in the control arm and 65.0% in the investigational arm using a one‐sided test at an α of .025 in a fixed sample design. These estimates were made based on the available balloon dilation literature and a study of the effectiveness of nasal steroids in treating ETD …”
Section: Methods
mentioning
confidence: 64%