Abstract:To the Editor We read with the great interest the systematic review and meta-analysis by de Almeida Leite and colleagues, 1 who suggest that nonoperative management of acute uncomplicated appendicitis (AUA) is comparable with surgery without an increase in major complications, albeit with a longer hospital stay and a cumulative appendicitis recurrence rate of 18%, highlighted by the authors as 2 major limitations of this treatment approach.The efficacy of antibiotic therapy in adults with AUA ranges from 63% t… Show more
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