Malnutrition in Children With Chronic Disease

Larson‐Nath, Catherine; Goday, Praveen S.

doi:10.1002/ncp.10274

Cited by 77 publications

(59 citation statements)

References 125 publications

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“…Furthermore, children with congenital heart anomalies often struggle with vomiting and feeding tolerance and consequently develop an oral aversion. Some well-understood postoperative risk factors for malnutrition in children with CHD are frequent interruptions of feeding, vocal cord dysfunction, chylothorax, and those with single ventricle disease that is at risk for experiencing a protein-losing enteropathy [7].…”

Section: Introductionmentioning

confidence: 99%

The Association between Cyanotic and Acyanotic Congenital Heart Disease with Nutritional Status

Amelia

Adriansyah

Lubis

et al. 2020

Open Access Maced J Med Sci

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BACKGROUND: Congenital heart disease (CHD) is one of the most common birth anomalies in the 1st year of life. The incidence of CHD in developed and developing countries is varied, between 6 and 10 cases per 1000 live birth. Some factors contribute to the nutritional status of CHD patients, such as nutrient inputs, energy requirements, and dietary components. Irrespective of the nature of the cardiac defect and the presence or absence of cyanosis, malnutrition is a common finding in children with congenital heart anomalies. Recent studies have tried to investigate malnutrition development based on the type or category of CHD. AIM: This study aims to investigate the association between cyanotic and acyanotic CHD with nutritional status. METHODS: A cross-sectional study was conducted from January to March 2018 in the pediatric cardiology outpatient clinic of the Haji Adam Malik General Hospital, Medan, Indonesia. RESULTS: During the study period, 58 children were admitted, consisting of 31 (53.4%) males and 27 (46.6%) females, with a mean age of 57 months. There was no significant sex predilection found in the study (p = 0.207). The proportion of patients who developed malnutrition was 70.7% (mild-moderate = 48.3% and severe = 22.4%). There was an association between cyanotic and acyanotic CHD with nutritional status (p = 0.015). Wasting was found in 33 children (56.8%) that had a significant association with the type of heart defects (p = 0.001). Patients with cyanotic CHDs were found to have a lower risk for malnutrition compared to the acyanotic group (prevalence odds ratio = 0.218, and prevalence risk = 0.661; p = 0.015). CONCLUSIONS: There is an association between cyanotic and acyanotic CHD with nutritional status.

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Section: Introductionmentioning

confidence: 99%

The Association between Cyanotic and Acyanotic Congenital Heart Disease with Nutritional Status

Amelia

Adriansyah

Lubis

et al. 2020

Open Access Maced J Med Sci

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“…The improvements in nutritional care, which have led to increased survival and well-being of many children with chronic disease, have been achieved by effective collaborations between scientists, clinicians, and industry [1]. However, in the critically important area of infant and young child nutrition in the general population, partnership working, especially between the WHO and the infant food industry, has a history of acrimony and division, and consequently infant feeding issues relating to policy and practice that were prominent 4 decades ago are still current today [2].…”

mentioning

confidence: 99%

Should There Be a Comprehensive Independent Review of Infant Feeding Policymaking?

Forsyth

2020

Ann Nutr Metab

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“…Children with chronic disease are at risk of malnutrition due to increased caloric needs, malabsorption, altered nutrient utilization and limitations in nutrient provision. The degree to which pubertal development is affected in chronic illness depends on the type of disease and its severity 26 . Undernutrition is associated with a significant delay in attaining pubertal levels of IGF‐1, LH, FSH and sex steroid hormones, as well as with low leptin levels 27 .…”

Section: Discussionmentioning

confidence: 99%

“…Undernutrition is associated with a significant delay in attaining pubertal levels of IGF‐1, LH, FSH and sex steroid hormones, as well as with low leptin levels 27 . In children affected by CF, risk factors for malnutrition are resting energy expenditure, chronic inflammation, malabsorption secondary to pancreatic insufficiency, fat‐soluble vitamin deficiencies, diabetes and decreased appetite 26 . It has been demonstrated that chronic inflammation in CF, despite good clinical status, is an important modulator of the IGF/IGFBP system, and it represents a possible mechanism for peripheral resistance to growth hormone (GH).…”

Section: Discussionmentioning

confidence: 99%

Delayed age at menarche in chronic respiratory diseases

Gaudino

Ben

Cavarzere

et al. 2020

Eur J Clin Investigation

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Objective: Age at menarche (AAM) is an important indicator of physiological development in women, and delayed AAM has been associated with chronic illnesses.We investigated predictive factors at diagnosis that influence AAM in adolescents with chronic respiratory diseases. Study design: AAM was assessed in 1207 northern Italian female aged 11-24 (1062 healthy, 98 with asthma and 47 with cystic fibrosis [CF]). AAM was defined by recall and status quo methods. We studied anthropometric data, metabolic status, diagnosis parameters, presence of irregular menses. Clinical data of subjects with chronic respiratory illness were compared with that of healthy adolescents. Results: Mean AAM for healthy adolescents was 12.49 ± 1.2 years. Mother's AAM was positively associated with that of their daughters (P < .001). BMI was negatively correlated with AAM (P < .001). 69% of healthy adolescents referred regular menses. AAM in the different groups was 12.79 ± 3.0 years for patients with asthma (P < .05 vs healthy) and 13.24 ± 1.44 years for adolescents with CF (P < .0001 vs healthy). In the asthmatic group, 57% of the patients referred regular menses, and no significant differences were found between AAM and control of the disease (ACT test). In the CF group, no correlation was found between the type of CFTR mutation or FEV1% and AAM. 53% of the patients with CF referred regular menses. Conclusions: AAM in patients with CF and asthma was significantly higher than in healthy adolescents, and menses abnormalities were observed in the last two groups.Inflammation influences the reproductive function in chronic respiratory disease.

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Malnutrition in Children With Chronic Disease

Cited by 77 publications

References 125 publications

The Association between Cyanotic and Acyanotic Congenital Heart Disease with Nutritional Status

The Association between Cyanotic and Acyanotic Congenital Heart Disease with Nutritional Status

Should There Be a Comprehensive Independent Review of Infant Feeding Policymaking?

Delayed age at menarche in chronic respiratory diseases

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