Malignant External Otitis

External otitis: Otological problems

“…The term Malignant external otitis is attributed to Chandler (1968) who reported thirteen cases with a mortality of approximately 50 per cent. A further four cases have been reported by Wilson, Pulec and Linthicum (1971) and two cases were presented to this Section last year by Evans (1972) occurring in this country. Fortunately, the disease has, so far, been uncommon in Britain, since it presents a most serious and challenging problem, but with the increasing resistance of the causative organism, Pseudomonas Pyocaneus, to the older generation of antibiotics, a fact noted by Chandler and probably by many of us, it is possible that more cases will be seen here and it is perhaps justifiable that brief reference should be made to it in this paper, though personal experience is limited to one case.…”

Masked diabetic mastoiditis

“…4). The findings of Chandler (1968Chandler ( , 1972 and Wilson et al (1971) of a dehiscence in the floor of the external canal from which granulations appear in the external canal may be explained either by an actual dehiscence or by a fistula produced by infection extending from these cells. Chandler (1972) reported another 26 cases of malignant external otitis, with an attempt to shed some light on the pathogenesis of facial palsy in this disease.…”

Histopathology of the soft parts in 50 patients with malignant external otitis

“…Malignant external otitis is a relatively recent clinical entity which has been described in detail in previous reports (Meltzer and Keleman, 1959;Chandler, 1968Chandler, , 1977. This is a severe external otitis which proceeds towards an infiltrating osteomyelitis of the skull base and may be lethal when untreated (Meltzer and Keleman, 1959;Chandler, 1968Chandler, , 1977Morgenstein and Seung, 1971;Wilson et al, 1971;Petrozzi, 1974;Nadol, 1980;Babiatzki and Sade, 1987). Today the survival rate is excellent when the basic underlying disease, such as diabetes mellitus, is adequately treated and when appropriate and prolonged antipseudomonal therapy is employed.…”