Male circumcision for prevention of heterosexual acquisition of HIV in men

The when and how of male circumcision and the risk of HIV: a retrospective cross-sectional analysis of two HIV surveys from Guinea-Bissau

“…In this study, we examined the association between MC, age and method of circumcision and the risk of HIV in Bissau, Guinea Bissau. Our findings are in line with the literature that has shown that MC is protective against HIV [ 8 – 11 ]. However, our data did not show increased protection based on early circumcision, contrary to previous research [ 23 ].…”

The when and how of male circumcision and the risk of HIV: a retrospective cross-sectional analysis of two HIV surveys from Guinea-Bissau

“…In this study, we examined the association between MC, age and method of circumcision and the risk of HIV in Bissau, Guinea Bissau. Our findings are in line with the literature that has shown that MC is protective against HIV [ 8 – 11 ]. However, our data did not show increased protection based on early circumcision, contrary to previous research [ 23 ].…”

Circumcision and the risk of prostate cancer

“…Circumcision is associated with a reduction in the risk of incident HIV 27. This is consistent with previous studies that have reported lower rates of different STIs (eg, HPV, herpes simplex, syphilis, chancroid) in circumcised men 45, 46.…”

“…This is consistent with previous studies that have reported lower rates of different STIs (eg, HPV, herpes simplex, syphilis, chancroid) in circumcised men 45, 46. The mechanism(s) by which circumcision reduces acquisition of an STI is thought to be related to the microenvironment of the thin, lightly keratinized mucosal lining of the inner foreskin 27, 47. This tissue is subject to small tears that allow potential access of pathogens to the bloodstream.…”

“…Circumcision is associated with a reduction in the risk of incident HIV. 27 This is consistent with previous studies that have reported lower rates of different STIs (eg, HPV, herpes simplex, syphilis, chancroid) in circumcised men. 45,46 The mechanism(s) by which circumcision reduces acquisition of an STI is thought to be related to the microenvironment of the thin, lightly keratinized mucosal lining of the inner foreskin.…”

Risk Factors for Recent HIV Infections among Adults in 14 Countries in Africa Identified by Population-Based HIV Impact Assessment Surveys, 2015–2019

“…Certain factors could not be included in the final model because those data were collected inconsistently across countries or were applicable only to subpopulations. However, voluntary medical male circumcision has been shown to reduce the risk of HIV acquisition by 38%–66% ( 27 ), and our bivariate comparisons of participants with recent infections compared with HIV-negative participants are consistent with those data. Additional analyses of PHIA data from fewer countries but using methods designed to specifically determine the effect of male medical circumcision on HIV incidence have similarly found a substantial protective effect, particularly among younger men and boys 15–34 years of age ( 28 ).…”

The when and how of male circumcision and the risk of HIV: a retrospective cross-sectional analysis of two HIV surveys from Guinea-Bissau

“…In this study, we examined the association between MC, age and method of circumcision and the risk of HIV in Bissau, Guinea Bissau. Our findings are in line with the literature that has shown that MC is protective against HIV [ 8 – 11 ]. However, our data did not show increased protection based on early circumcision, contrary to previous research [ 23 ].…”

Circumcision and the risk of prostate cancer

“…Circumcision is associated with a reduction in the risk of incident HIV 27. This is consistent with previous studies that have reported lower rates of different STIs (eg, HPV, herpes simplex, syphilis, chancroid) in circumcised men 45, 46.…”

“…This is consistent with previous studies that have reported lower rates of different STIs (eg, HPV, herpes simplex, syphilis, chancroid) in circumcised men 45, 46. The mechanism(s) by which circumcision reduces acquisition of an STI is thought to be related to the microenvironment of the thin, lightly keratinized mucosal lining of the inner foreskin 27, 47. This tissue is subject to small tears that allow potential access of pathogens to the bloodstream.…”

“…Circumcision is associated with a reduction in the risk of incident HIV. 27 This is consistent with previous studies that have reported lower rates of different STIs (eg, HPV, herpes simplex, syphilis, chancroid) in circumcised men. 45,46 The mechanism(s) by which circumcision reduces acquisition of an STI is thought to be related to the microenvironment of the thin, lightly keratinized mucosal lining of the inner foreskin.…”

Risk Factors for Recent HIV Infections among Adults in 14 Countries in Africa Identified by Population-Based HIV Impact Assessment Surveys, 2015–2019

“…Certain factors could not be included in the final model because those data were collected inconsistently across countries or were applicable only to subpopulations. However, voluntary medical male circumcision has been shown to reduce the risk of HIV acquisition by 38%–66% ( 27 ), and our bivariate comparisons of participants with recent infections compared with HIV-negative participants are consistent with those data. Additional analyses of PHIA data from fewer countries but using methods designed to specifically determine the effect of male medical circumcision on HIV incidence have similarly found a substantial protective effect, particularly among younger men and boys 15–34 years of age ( 28 ).…”

The when and how of male circumcision and the risk of HIV: a retrospective cross-sectional analysis of two HIV surveys from Guinea-Bissau

“…In this study, we examined the association between MC, age and method of circumcision and the risk of HIV in Bissau, Guinea Bissau. Our findings are in line with the literature that has shown that MC is protective against HIV [ 8 – 11 ]. However, our data did not show increased protection based on early circumcision, contrary to previous research [ 23 ].…”

Circumcision and the risk of prostate cancer

“…Circumcision is associated with a reduction in the risk of incident HIV 27. This is consistent with previous studies that have reported lower rates of different STIs (eg, HPV, herpes simplex, syphilis, chancroid) in circumcised men 45, 46.…”

“…This is consistent with previous studies that have reported lower rates of different STIs (eg, HPV, herpes simplex, syphilis, chancroid) in circumcised men 45, 46. The mechanism(s) by which circumcision reduces acquisition of an STI is thought to be related to the microenvironment of the thin, lightly keratinized mucosal lining of the inner foreskin 27, 47. This tissue is subject to small tears that allow potential access of pathogens to the bloodstream.…”

“…Circumcision is associated with a reduction in the risk of incident HIV. 27 This is consistent with previous studies that have reported lower rates of different STIs (eg, HPV, herpes simplex, syphilis, chancroid) in circumcised men. 45,46 The mechanism(s) by which circumcision reduces acquisition of an STI is thought to be related to the microenvironment of the thin, lightly keratinized mucosal lining of the inner foreskin.…”

Risk Factors for Recent HIV Infections among Adults in 14 Countries in Africa Identified by Population-Based HIV Impact Assessment Surveys, 2015–2019

“…Certain factors could not be included in the final model because those data were collected inconsistently across countries or were applicable only to subpopulations. However, voluntary medical male circumcision has been shown to reduce the risk of HIV acquisition by 38%–66% ( 27 ), and our bivariate comparisons of participants with recent infections compared with HIV-negative participants are consistent with those data. Additional analyses of PHIA data from fewer countries but using methods designed to specifically determine the effect of male medical circumcision on HIV incidence have similarly found a substantial protective effect, particularly among younger men and boys 15–34 years of age ( 28 ).…”