Male breast cancer: Risk factors, diagnosis, and management (Review)

Taber, Johansen

doi:10.3892/or_00000962

Cited by 89 publications

(41 citation statements)

References 47 publications

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“…A history of MBC is associated with a 30 fold increased risk on the contralateral side, which is much higher than the increase of 2 to 4-fold observed in women. (Meijers-Heijboer et al, 2002;Levy-Lahad et al, 2007;Lanitis et al, 2008;Mohamad et al, 2008;Daly et al, 2009;Ottini et al, 2009;Ottini et al, 2010;Taber Johansen et al, 2010).…”

Section: Risk Factorsmentioning

confidence: 99%

Male Breast Carcinoma: Epidemiology, Risk Factors and Current Therapeutic Approaches

Zygogianni

Kyrgias²,

Gennatas³

et al. 2012

Asian Pacific Journal of Cancer Prevention

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Male breast cancer is a very rare disease with an incidence of about 0.5-1% comparing with the one of female breast cancer but relatively little is known about its cause. Treatment strategies for breast cancer in males are derived from studies performed among females. The probable reasons behind the frequent, late diagnoses presented at stages III or IV might be the lack of awareness. The rarity of the disease precludes large prospective randomized clinical trials. This study reviews male breast cancer and its risk factors, recommendations for diagnosis and the management of patients with male breast cancer.

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Section: Risk Factorsmentioning

confidence: 99%

Male Breast Carcinoma: Epidemiology, Risk Factors and Current Therapeutic Approaches

Zygogianni

Kyrgias²,

Gennatas³

et al. 2012

Asian Pacific Journal of Cancer Prevention

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“…Risk factors for male bc include family history, increased estrogen exposure, androgen deficiency (for example, in Klinefelter syndrome, liver cirrhosis, and obesity), radiation exposure, certain occupational exposures 3 , and inherited BRCA 4 gene mutations. It is estimated that men with BRCA2 mutations carry a 6.8% lifetime risk-102 times the risk in the general populationof developing bc 5 .…”

Section: Introductionmentioning

confidence: 99%

Treatment Outcomes for Male Breast Cancer: A Single-Centre Retrospective Case–Control Study

et al. 2014

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Background: Male breast cancer (bc) is a rare disease, and the availability of information on treatment outcomes is limited compared with that for female bc. The objective of the present study was to compare disease-free (dfs) and overall survival (os) for men compared with women having early-stage bc. Methods: This retrospective case–control study compared men and women treated for stage 0–iiib bc at a single institution between 1981 and 2009. Matching was based on age at diagnosis, year of diagnosis, and stage. Treatment, recurrence, and survival data were collected. Kaplan–Meier analysis was used to calculate os and dfs. Results: For the 144 eligible patients (72 men, 72 women), median age at diagnosis was 66.5 years. Treatments included mastectomy (72 men, 38 women), radiation (29 men, 44 women), chemotherapy (23 men, 20 women), and endocrine therapy (57 men, 57 women). Mean dfs was 127 months for women compared with 93 months for men (p = 0.62). Mean os was 117 months for women compared with 124 months for men (p = 0.35). In multivariate analysis, the only parameter that affected both dfs and os was stage at diagnosis. Conclusions: This case–control study is one of the largest to report treatment outcomes in early-stage male bc patients treated in a non-trial setting. Male patients received systemic therapy that was comparable to that received by their female counterparts, and they had similar os and dfs. These results add to current evidence from population studies that male sex is not a poor prognostic factor in early-stage breast cancer.

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“…Although it is thought to be a disease typical in women, about 1% of all breast cancers appears in men (1,2). While it occurs in men aged 65 years on average, its incidence shows a peak at the ages of 68-71 years (3,4). It has been reported men perceive that breast cancer is an illness that occurs mainly later in life (5).…”

Section: Introductionmentioning

confidence: 99%

Validity and Reliability of Turkish Male Breast Self-Examination Instrument

Erkin

Göl

2018

Eur J Breast Health

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Objective: This study aims to measure the validity and reliability of Turkish male breast self-examination (MBSE) instrument. Materials and Methods:The methodological study was performed in 2016 at Ege University, Faculty of Nursing, İzmir, Turkey. The MBSE includes ten steps. For validity studies, face validity, content validity, and construct validity (exploratory factor analysis) were done. For reliability study, Kuder Richardson was calculated. Results:The content validity index was found to be 0.94. Kendall W coefficient was 0.80 (p=0.551). The total variance explained by the two factors was found to be 63.24%. Kuder Richardson 21 was done for reliability study and found to be 0.97 for the instrument. The final instrument included 10 steps and two stages. Conclusions:The Turkish version of MBSE is a valid and reliable instrument for early diagnose. The MBSE can be used in Turkish speaking countries and cultures with two stages and 10 steps.

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Male breast cancer: Risk factors, diagnosis, and management (Review)

Cited by 89 publications

References 47 publications

Male Breast Carcinoma: Epidemiology, Risk Factors and Current Therapeutic Approaches

Male Breast Carcinoma: Epidemiology, Risk Factors and Current Therapeutic Approaches

Treatment Outcomes for Male Breast Cancer: A Single-Centre Retrospective Case–Control Study

Validity and Reliability of Turkish Male Breast Self-Examination Instrument

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