DOI: 10.1101/2020.06.19.160929
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Abstract: 11 12 13 14 15 47 The Janus kinase (JAK)/signal transducer and activator of transcription (STAT) signaling 48 system is of central importance for several critical physiological processes including 49 development, tissue homeostasis, and immune responses [1]. Various cytokines, growth 50 factors, and related signaling compounds signal via this evolutionarily conserved system 51 [2]. The JAK/STAT signaling pathway effectively transduces external signals into desired 52 cellular responses despite having relativel… Show more

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