Main Traits of Breast Fibroadenoma Among Adolescent Girls

Sun, Chunjie; Zhang, Wanlong; Ma, Haihui; Han, Na Mi; Qi, Menghu; Dong-lian, LI; Wang, Xiaojing; Wang, Xuehui; Yang, Jie

doi:10.1089/cbr.2019.3209

Cited by 4 publications

(7 citation statements)

References 26 publications

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“…Фиброаденомы молочных желез являются самым частым вариантом соединительнотканно-эпителиальных опухолей и составляют до 20% всех патологических образований молочной железы [4,13,16]. Обычно это единичные образования, но в 15% случаев отмечается множественный характер поражения [17]. Фиброаденомы молочных желез обнаруживают во всех возрастных группах, но наиболее часто -в возрасте до 20-35 лет [2,16,17].…”

Section: фиброаденома молочной железыunclassified

“…Обычно это единичные образования, но в 15% случаев отмечается множественный характер поражения [17]. Фиброаденомы молочных желез обнаруживают во всех возрастных группах, но наиболее часто -в возрасте до 20-35 лет [2,16,17].…”

Section: фиброаденома молочной железыunclassified

“…Опухоль четко отграничена от окружающих тканей, а выраженность фиброза стромы определяет ее консистенцию. Гистологически это двухкомпонентное образование, представленное как эпителиальными, так и соединительнотканными структурами [17].…”

Section: фиброаденома молочной железыunclassified

“…Во всех остальных случаях может быть рекомендовано динамическое наблюдение. Последнее обусловлено еще и тем, что злокачественная трансформация фиброаденом наблюдается редко [12,17]. Прогноз в целом благоприятный.…”

Section: фиброаденома молочной железыunclassified

“…Кожа над образованием может истончаться и изъязвляться, часто отмечают серозные выделения из соска (рис. 3) [17,19]. Для листовидных опухолей характерна двухфазность клинического течения, при котором «фаза относительного покоя» сменяется этапом бурного роста.…”

Section: листовидная опухольunclassified

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Focal Pathology of Mammary Glands in Teenage Girls

Высоцкая

Летягин

Воротников

et al. 2020

Vopr. sovr. pediatr.

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Diseases of the mammary glands (usually benign) have the incidence of 5–12% in the structure of children diseases. Breast cancer is extremely rare (less than 1% of all breast diseases). This review contains actual data on the most common focal pathology of mammary glands in teenage girls such as: focal hyperplasia, cysts and breast fibroepithelial tumors. Clinical manifestations, morphological picture and diagnostics are described. Main approaches to treatment of patients with focal pathology of mammary glands are defined. The presented data is crucial for timely diagnosis of focal pathology of mammary glands, selection of examination tactics, management and necessary measures for oncological diseases prevention in children.

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Section: фиброаденома молочной железыunclassified

Section: листовидная опухольunclassified

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Focal Pathology of Mammary Glands in Teenage Girls

Высоцкая

Летягин

Воротников

et al. 2020

Vopr. sovr. pediatr.

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Correlation analysis of breast fibroadenoma and the intestinal flora based on 16S rRNA sequencing*

Wang

Liu

Bian

et al. 2021

Oncology and Translational Medicine

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ObjectiveTo analyze the characteristics of the intestinal microflora in patients with breast fibroadenoma using 16S ribosomal RNA (rRNA) high-throughput sequencing.MethodsFecal samples from 20 patients with breast fibroadenoma and 36 healthy subjects were randomly collected and analyzed using high-throughput sequencing technology for 16S rRNA V4 region sequencing, and the alpha diversity (Chao index, Shannon index) was calculated using Mothur (v.1.39.5) software. Beta diversity was analyzed using QIIME (v1.80). SPSS software (version 23.0) and the t-test of two independent samples were used to analyze differences in the abundance of bacteria between the two groups.ResultsCompared with that in the healthy control group, the α diversity of the intestinal microflora in breast fibroadenoma patients increased, but the difference was not statistically significant (P > 0.05). At the phylum level, significant differences were observed between the two groups. The abundance of Firmicutes was higher in the breast fibroadenoma group (P < 0.05), whereas the abundance of Synergistetes was higher in the healthy control group (P < 0.005). A total of five bacterial genera showed significant differences between the two groups: the breast fibroadenoma group showed higher levels of Bautia (P < 0.005), Coprococcus (P < 0.005), Roseburia (P < 0.05), and Ruminococcus (P < 0.005), whereas Sutterella was more abundant in the healthy control group than in the breast fibroadenoma group (P < 0.05).ConclusionThe diversity and abundance of the intestinal flora in patients with breast fibroadenoma are significantly different from those in healthy subjects, suggesting that an imbalance in the intestinal flora is correlated with the occurrence of breast fibroadenoma.

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Comparison of Pericanalicular and Intracanalicular Fibroadenoma Mammae Growth Pattern on Various Age Range

Utamie,

Ningrom,

Handoyo Sakti

et al. 2023

magnamed

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Background: Fibroadenoma mammae is the most common type of benign breast tumor in women. Fibroadenoma mammae can occur on various ages, there is no much data recorded about anatomical pathology especially regarding the distribution of fibroadenoma mammae growth pattern in Siaga Medika Purbalingga Hospital. Study in Indonesia that focus on this topic also remain scarce.Objective: To analyze comparison between the growth pattern in fibroadenoma mammae patients with age range 11-50 years.Method: This cross-sectional study with data collected restrospectively based on medical records and histopatological examination in Siaga Medika Purbalingga Hospital. Statistical analysis was done using JASP 0.14.1.0.Results: The majority of patients with fibroadenoma mammae were in the age range 21-30 years (48.9%) with pericanalicular pattern (66%). The four groups had different two growth pattern (p <0.001). Odds ratio showed 3.4 that means patient with age ≤30 years has chance 3.4x to diagnose with pericanalicular fibroadenoma mammae than patient with age >30 years.Conclusion: Incidence of pericanalicular and intracanalicular fibroadenoma mammae growth pattern in Siaga Medika Purbalingga Hospital patients can be affected by age.

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Main Traits of Breast Fibroadenoma Among Adolescent Girls

Cited by 4 publications

References 26 publications

Focal Pathology of Mammary Glands in Teenage Girls

Focal Pathology of Mammary Glands in Teenage Girls

Correlation analysis of breast fibroadenoma and the intestinal flora based on 16S rRNA sequencing*

Comparison of Pericanalicular and Intracanalicular Fibroadenoma Mammae Growth Pattern on Various Age Range

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