Magnetic Resonance Imaging Hyperintensities in Alzheimer's Disease-Reply

Leuko-Araiosis: Relationship with the Types of Focal Lesions Occurring in Acute Cerebrovascular Disorders

“…These surprising high k values might be explained by the small number of patients with each abnormality. This might have skewed our results towards more agreements since a good agree ment is more likely to occur among subjects with a low prevalence of the abnormality [29,30], especially with such simple scoring schemes [29,30].…”

Leuko-Araiosis: Relationship with the Types of Focal Lesions Occurring in Acute Cerebrovascular Disorders

“…These surprising high k values might be explained by the small number of patients with each abnormality. This might have skewed our results towards more agreements since a good agree ment is more likely to occur among subjects with a low prevalence of the abnormality [29,30], especially with such simple scoring schemes [29,30].…”

Magnetic Resonance Imaging of Neurodegenerative Diseases

“…Only limited correlation between MRI signal abnormalities and clinical status has been identified. McDonald and coworkers [88] and Leys and associates [89] did not find a correlation between Mini-Mental State Examination scores and the presence of WMHs or PVHs in AD patients. Using a more detailed neuropsychological evaluation, Harrell and colleagues [82] found cognitive function to be more impaired in demented patients with severe PVH.…”

Leuko-Araiosis: Relationship with the Types of Focal Lesions Occurring in Acute Cerebrovascular Disorders

“…These surprising high k values might be explained by the small number of patients with each abnormality. This might have skewed our results towards more agreements since a good agree ment is more likely to occur among subjects with a low prevalence of the abnormality [29,30], especially with such simple scoring schemes [29,30].…”

Magnetic Resonance Imaging of Neurodegenerative Diseases

“…Only limited correlation between MRI signal abnormalities and clinical status has been identified. McDonald and coworkers [88] and Leys and associates [89] did not find a correlation between Mini-Mental State Examination scores and the presence of WMHs or PVHs in AD patients. Using a more detailed neuropsychological evaluation, Harrell and colleagues [82] found cognitive function to be more impaired in demented patients with severe PVH.…”

Leuko-Araiosis: Relationship with the Types of Focal Lesions Occurring in Acute Cerebrovascular Disorders

“…These surprising high k values might be explained by the small number of patients with each abnormality. This might have skewed our results towards more agreements since a good agree ment is more likely to occur among subjects with a low prevalence of the abnormality [29,30], especially with such simple scoring schemes [29,30].…”

Magnetic Resonance Imaging of Neurodegenerative Diseases

“…Only limited correlation between MRI signal abnormalities and clinical status has been identified. McDonald and coworkers [88] and Leys and associates [89] did not find a correlation between Mini-Mental State Examination scores and the presence of WMHs or PVHs in AD patients. Using a more detailed neuropsychological evaluation, Harrell and colleagues [82] found cognitive function to be more impaired in demented patients with severe PVH.…”