Magnetic Resonance Direct Thrombus Imaging in Moderate Carotid Artery Stenosis

Abstract

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Ex vivo study of carotid endarterectomy specimens: quantitative relaxation times within atherosclerotic plaque tissues

“…Our study also reported no discernable hemorrhage post-sectioning. Fortunately, the intra-plaque contrast properties of calcium and hemorrhage have previously been established [26,27]. Ultra short echo time sequences have separately been applied to quantify calcium [28].…”

Discriminating Carotid Atherosclerotic Lesion Severity by Luminal Stenosis and Plaque Burden

“…A better-designed future study may include a larger sample size, homogenous inclusion criteria and imaging protocol, multiple races, and fair gender distribution. Additionally, the new developed imaging techniques for detecting IPH 29 and thrombus 30 might be helpful in characterizing vulnerable plaques in future studies.…”

Characterisation of carotid atheroma in symptomatic and asymptomatic patients using high resolution MRI

“…For example, Takaya et al showed that among patients who initially had an asymptomatic 50–79% carotid stenosis, arteries with thinned or ruptured fibrous caps, intraplaque haemorrhage or large lipid rich/necrotic cores, by MRI, were associated with the occurrence of subsequent cerebrovascular events 23. Similarly, Daniels et al showed the potential value of MRI and detection of intraplaque haemorrhage in decision making for moderate carotid stenosis 24. Our study supports these findings and adds weight to the argument that plaque characterisation with MRI is a potentially valuable clinical tool for risk stratification.…”