Magnesium sulphate versus phenytoin for eclampsia

A prospective study of the incidence and outcomes of eclampsia in a tertiary care hospital and teaching institute in India

“…For prevention of recurrent convulsions in patients diagnosed with eclampsia, it has been shown in systematic reviews that magnesium sulphate is safer and more effective than phenytoin, diazepam or lytic cocktail. [34][35][36] In our study, we found that magnesium sulphate was effective in 90% of cases for the same, thus strengthening the previous recommendation about this treatment.…”

A prospective study of the incidence and outcomes of eclampsia in a tertiary care hospital and teaching institute in India

“…For prevention of recurrent convulsions in patients diagnosed with eclampsia, it has been shown in systematic reviews that magnesium sulphate is safer and more effective than phenytoin, diazepam or lytic cocktail. [34][35][36] In our study, we found that magnesium sulphate was effective in 90% of cases for the same, thus strengthening the previous recommendation about this treatment.…”

Magnesium sulphate versus phenytoin in eclampsia – Maternal and foetal outcome –

“…Perinatal mortality rate (PNMR) in Group M was 278 per 1000 births, slightly more than PNMR of Group-P with 235 per 1000 births. This finding was corroborated by Buckshee et al 32 who mentioned PNMR of 23.3 per cent in the phenytoin treated group. However, another study 31 found out that fewer babies died to mothers treated with magnesium sulphate.…”

A Clinical Study of 100 Cases of Eclampsia and 50 Cases of Severe Preeclampsia With Outcome of Treatment With Magnesium Sulphate and Keeping Lytic Cocktail as Control in 10 Cases of Eclampsia

“…To conclude, it can be emphasised that magnesium sulphate is the drug of choice for the prophylactic (Duley 2003a) [9] as well as therapeutic management of severe preeclampsia and eclampsia respectively (Duley 2003b;Duley 2003c). [10,11] It is very efficient in the prevention of fits in severe preeclampsia and reduction in recurrence of fits in eclampsia. MgSO4 is also efficient in reducing maternal morbidity and mortality.…”

A prospective study of the incidence and outcomes of eclampsia in a tertiary care hospital and teaching institute in India

“…For prevention of recurrent convulsions in patients diagnosed with eclampsia, it has been shown in systematic reviews that magnesium sulphate is safer and more effective than phenytoin, diazepam or lytic cocktail. [34][35][36] In our study, we found that magnesium sulphate was effective in 90% of cases for the same, thus strengthening the previous recommendation about this treatment.…”

Magnesium sulphate versus phenytoin in eclampsia – Maternal and foetal outcome –

“…Perinatal mortality rate (PNMR) in Group M was 278 per 1000 births, slightly more than PNMR of Group-P with 235 per 1000 births. This finding was corroborated by Buckshee et al 32 who mentioned PNMR of 23.3 per cent in the phenytoin treated group. However, another study 31 found out that fewer babies died to mothers treated with magnesium sulphate.…”

A Clinical Study of 100 Cases of Eclampsia and 50 Cases of Severe Preeclampsia With Outcome of Treatment With Magnesium Sulphate and Keeping Lytic Cocktail as Control in 10 Cases of Eclampsia

“…To conclude, it can be emphasised that magnesium sulphate is the drug of choice for the prophylactic (Duley 2003a) [9] as well as therapeutic management of severe preeclampsia and eclampsia respectively (Duley 2003b;Duley 2003c). [10,11] It is very efficient in the prevention of fits in severe preeclampsia and reduction in recurrence of fits in eclampsia. MgSO4 is also efficient in reducing maternal morbidity and mortality.…”

A prospective study of the incidence and outcomes of eclampsia in a tertiary care hospital and teaching institute in India

“…For prevention of recurrent convulsions in patients diagnosed with eclampsia, it has been shown in systematic reviews that magnesium sulphate is safer and more effective than phenytoin, diazepam or lytic cocktail. [34][35][36] In our study, we found that magnesium sulphate was effective in 90% of cases for the same, thus strengthening the previous recommendation about this treatment.…”

Magnesium sulphate versus phenytoin in eclampsia – Maternal and foetal outcome –

“…Perinatal mortality rate (PNMR) in Group M was 278 per 1000 births, slightly more than PNMR of Group-P with 235 per 1000 births. This finding was corroborated by Buckshee et al 32 who mentioned PNMR of 23.3 per cent in the phenytoin treated group. However, another study 31 found out that fewer babies died to mothers treated with magnesium sulphate.…”

A Clinical Study of 100 Cases of Eclampsia and 50 Cases of Severe Preeclampsia With Outcome of Treatment With Magnesium Sulphate and Keeping Lytic Cocktail as Control in 10 Cases of Eclampsia

“…To conclude, it can be emphasised that magnesium sulphate is the drug of choice for the prophylactic (Duley 2003a) [9] as well as therapeutic management of severe preeclampsia and eclampsia respectively (Duley 2003b;Duley 2003c). [10,11] It is very efficient in the prevention of fits in severe preeclampsia and reduction in recurrence of fits in eclampsia. MgSO4 is also efficient in reducing maternal morbidity and mortality.…”