Magnesium and fluoride doped hydroxyapatite coatings grown by pulsed laser deposition for promoting titanium implant cytocompatibility

Cao, Jinxing; Lian, Ruizhe

doi:10.1016/j.apsusc.2020.146069

Cited by 48 publications

(24 citation statements)

References 43 publications

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“…Magnésio (Mg 2+ ), zinco (Zn 2+ ), manganês (Mn 2+ ), estrôncio (Sr 2+ ), cobre(Cu 2+ ), cério (Ce 3+ ), prata(Ag + ), flúor(F -) são alguns substitutos iônicos comumente utilizados como dopantes conferindo a HAp diferentes atividades biológicas (Cao et al, 2020;Wu et al, 2020;Zhou et al, 2020;Mahmood et al, 2020). Esses dopantes podem substituir parcialmente os cátions Ca 2+ , bem como os ânions OHe PO 4…”

Section: Dopagem Da Hidroxiapatitaunclassified

“…O íon fluoreto (F -) pode promover a nucleação do HAp e substituir OHno HAp para formar fluorapatita, que possui boa rigidez, alto módulo de elasticidade e dureza, pode ainda estimular a diferenciação de células-tronco mesenquimais em osteoblastos. (Cao et al, 2020), além disso pode reduzir a formação de cárie em ambientes contaminados por bactérias e promover a mineralização e cristalização de fosfatos de cálcio na formação óssea (Trewin et al, 2013).…”

Section: Novas Perspectivasunclassified

See 1 more Smart Citation

Síntese De Hidroxiapatita via Rota Pechini: Uma Breve Revisão

Almeida¹,

Costa²,

Farias³

et al. 2022

Análise E Desenvolvimento De Materiais Cerâmicos: Novas Perspectivas

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Section: Dopagem Da Hidroxiapatitaunclassified

Section: Novas Perspectivasunclassified

Síntese De Hidroxiapatita via Rota Pechini: Uma Breve Revisão

Almeida¹,

Costa²,

Farias³

et al. 2022

Análise E Desenvolvimento De Materiais Cerâmicos: Novas Perspectivas

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“…Calcium phosphates, especially HA, are widely used in the coating of metallic biomaterials to combine their biocompatibility and bioactivity properties with the mechanical strength of metals. There are also numerous studies about various ion-doped HA coatings on metallic substrates, some examples are strontium-doped [1], selenium-doped [2], magnesium and silver codoped [32], magnesium and fluoride co-doped [33] HA coatings on titanium or its alloys. However, the use of boron-incorporated HA as a coating material has been addressed in very few publications.…”

Section: Boron-doped Ha As a Coating Materialsmentioning

confidence: 99%

Boron doped Hydroxapatites in Biomedical Applications

Uysal¹,

Yılmaz²,

Evis³

2020

Journal of Boron

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Hydroxyapatite has been widely used in biomedical applications as a coating material for implant surfaces, a drug carrier, a scaffold or composite for bone tissue engineering applications. The highly ionic structure of hydroxyapatite allows doping of various ions, resulting in an improvement in its properties. Boron is one of the elements which can be doped into hydroxyapatite structure by replacing phosphate (PO 4 3-) or hydroxyl (OH-) sites to obtain scaffolds for bone tissue engineering applications or a coating material for metal substrates. Although the effects of supplemental boron on bone, liver, and brain metabolism have been shown to have important results as a nutrient, there are very few studies in the literature on the use of boron-doped hydroxyapatite in the biomedical field. In this review, the details of synthesis methods and functional groups of boron-doped hydroxyapatite were tabulated. Generally, the addition of boron leads to the formation of rod-like morphology, while the density and Vicker's microhardness of hydroxyapatite decrease. Thermal stability and electrical insulation properties were observed to improve with boron doping. Boron was also shown to increase biodegradability, bioactivity as well as cell proliferation and differentiation of different cell types on the surface of hydroxyapatite.

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“…Prolongation of the implant's life cycle inside the body has been extensively studied [9]. The majority of reports are based on surface expansion to fix the implant properly and then to increase corrosion resistance [10], i.e., grinding, etching, laser surface texturing [11], plasma spraying, etc., [12] combined with various coatings, i.e., Ti, TiN, TiO 2 [13], Zr, ZrO 2 [14], hydroxyapatite (HAp) [15], and Al 2 O 3 [16] . Hybrid treatment of implant materials is aimed at providing adequate influence of the surrounding tissues, and among many properties, the most important is significantly enhanced corrosion resistance [17].…”

Section: Introductionmentioning

confidence: 99%

The influence of plasma-sprayed coatings on surface properties and corrosion resistance of 316L stainless steel for possible implant application

Woźniak

Staszuk

Reimann

et al. 2021

Archiv.Civ.Mech.Eng

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Herein, we analyzed the morphology of atmospheric plasma-sprayed (APS) coating on medical 316L stainless steel and its influence on the physical and electrochemical properties of implant application. Five types of coatings were examined: hydroxyapatite (HAp), titanium (Ti), zirconium (Zr), Ti/HAp and Zr/HAp. The base properties of the coatings were analyzed via chemical and phase composition, surface topography, surface wettability and in particular the corrosion resistance in Ringer solution in immersed conditions and potentiodynamic test, and EIS analysis. APS coating of pure HAp on 316L stainless steel showed poor cohesive bonding to the substrate material, whereas the application of Ti and Zr interlayer prior to HAp deposition improved surface morphology and coating properties. The beneficial effect of Ti and Zr interlayer under HAp layer on binding was demonstrated. HAp containing coatings (HAp, Ti/HAp and Zr/HAp) show Ca/P ratio greater than 1.8, which may positively influence the differentiation of osteogenic cells and good adhesion to bones. Among the studied materials, the composite coatings with Zr or Zr/HAp showed favorable physicochemical properties and the highest corrosion resistance in Ringer solution.

show abstract

Magnesium and fluoride doped hydroxyapatite coatings grown by pulsed laser deposition for promoting titanium implant cytocompatibility

Cited by 48 publications

References 43 publications

Síntese De Hidroxiapatita via Rota Pechini: Uma Breve Revisão

Síntese De Hidroxiapatita via Rota Pechini: Uma Breve Revisão

Boron doped Hydroxapatites in Biomedical Applications

The influence of plasma-sprayed coatings on surface properties and corrosion resistance of 316L stainless steel for possible implant application

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