Macular Thickness Variations with Sex, Age, and Axial Length in Healthy Subjects: A Spectral Domain–Optical Coherence Tomography Study

Abstract

In normal subjects, SD-OCT showed that retinal thickness is related to age, sex, and axial length, with regional variations.

Evaluation of myopia on retinal nerve fiber layer thickness measured by Spectralis optical coherence tomography

“…Age and sex are two factors that may affect macular retinal thickness and RNFL thickness; however, contradictory results have been found in former studies (21,(23)(24)(25). In the present research, a statistically meaningful negative correlation was demonstrated between the global mean peripapillary RNFL thickness and age, which has been reported before in various studies (15,16).…”

Macular thickness and volume of myopic eyes measured using spectral‐domain optical coherence tomography

“…[6][7][8][9][10][11][12][13][14][15] In previous studies, the association between refractive error/AL and macular thickness/volume showed inconsistent results in terms of regional variations. For example, some studies [6][7][8] described significant correlation between refractive error/AL and macular measurements in inner retinal areas, whereas other studies [9][10][11][12] showed nonsignificant correlation in those areas.…”

Changes of Drusen Number and Central Retinal Thickness in Age-Related Macular Degeneration Patients Over Two Years

“…In this context, our result might not be associated to ARMD but rather to being female [22][23][24][25] . Some authors argue that thinner macula in women might be attributed to hormonal changes in menopause and even propose that female gender could be a risk factor for other macula diseases such as macular holes 26,27 . In the Beaver Dam Eye Study, macular thickness in women taking oral estrogen was on average 4 μm greater than in women not taking oral estrogen, although this difference did not reach statistical signifi cance 23 .…”