Lysophosphatidyl choline in the aqueous humour during ocular inflammation.

A Post-Operative Follow-Up of an Endangered Saltwater Fish Lensectomy for Cataract Management in a Public Aquarium: A Case Series

“…On average, choline intake was 1642% (1478-1793%) higher than the nutritional requirements. Choline excess could induce cataracts via an increased permeability of the lens [38]; thus, a nutritional etiology was suspected. The transition to a new diet based on balanced commercial pellets is ongoing in this aquarium.…”

A Post-Operative Follow-Up of an Endangered Saltwater Fish Lensectomy for Cataract Management in a Public Aquarium: A Case Series

“…On average, choline intake was 1642% (1478-1793%) higher than the nutritional requirements. Choline excess could induce cataracts via an increased permeability of the lens [38]; thus, a nutritional etiology was suspected. The transition to a new diet based on balanced commercial pellets is ongoing in this aquarium.…”

Relationship between the lipidome profile and disease activity in patients with rheumatoid arthritis

“…Lysophosphatidylcholine is known to exert pro-in ammatory effects. It is highly expressed at in ammatory sites [23], and its expression is followed by in ammatory responses to lysophosphatidylcholine in various cells. A stimulation with lysophosphatidylcholine induced in ammatory responses, such as the expression of adhesion molecules and production of COX-2, in vascular endothelial cells [24], chemotaxis, and proin ammatory cytokine production in monocytic cells [25], and evoked T-cell chemotaxis [26].…”

Mechanisms and Treatment of Light-Induced Retinal Degeneration-Associated Inflammation: Insights from Biochemical Profiling of the Aqueous Humor

“…Consistently, in our model, LIRD is associated with prolonged upregulation of lyso-PAF. Furthermore, PAF can be produced from lyso-PAF (by Lyso-PAF:acetyl-coenzyme A acetyltransferase) or from lysophosphatidyl choline (lyso-PC; biosynthesized by phospolipase A2), the concentration of which also increases in AH during ocular inflammation [57]. Given all of these data, it is not surprising that, in our model, LIRD is associated with prolonged growth in AH concentration of prostaglandins, among which PGF 2α remained elevated, even at the seventh day post-exposure.…”

A Post-Operative Follow-Up of an Endangered Saltwater Fish Lensectomy for Cataract Management in a Public Aquarium: A Case Series

“…On average, choline intake was 1642% (1478-1793%) higher than the nutritional requirements. Choline excess could induce cataracts via an increased permeability of the lens [38]; thus, a nutritional etiology was suspected. The transition to a new diet based on balanced commercial pellets is ongoing in this aquarium.…”

Relationship between the lipidome profile and disease activity in patients with rheumatoid arthritis

“…Lysophosphatidylcholine is known to exert pro-in ammatory effects. It is highly expressed at in ammatory sites [23], and its expression is followed by in ammatory responses to lysophosphatidylcholine in various cells. A stimulation with lysophosphatidylcholine induced in ammatory responses, such as the expression of adhesion molecules and production of COX-2, in vascular endothelial cells [24], chemotaxis, and proin ammatory cytokine production in monocytic cells [25], and evoked T-cell chemotaxis [26].…”

Mechanisms and Treatment of Light-Induced Retinal Degeneration-Associated Inflammation: Insights from Biochemical Profiling of the Aqueous Humor

“…Consistently, in our model, LIRD is associated with prolonged upregulation of lyso-PAF. Furthermore, PAF can be produced from lyso-PAF (by Lyso-PAF:acetyl-coenzyme A acetyltransferase) or from lysophosphatidyl choline (lyso-PC; biosynthesized by phospolipase A2), the concentration of which also increases in AH during ocular inflammation [57]. Given all of these data, it is not surprising that, in our model, LIRD is associated with prolonged growth in AH concentration of prostaglandins, among which PGF 2α remained elevated, even at the seventh day post-exposure.…”

A Post-Operative Follow-Up of an Endangered Saltwater Fish Lensectomy for Cataract Management in a Public Aquarium: A Case Series

“…On average, choline intake was 1642% (1478-1793%) higher than the nutritional requirements. Choline excess could induce cataracts via an increased permeability of the lens [38]; thus, a nutritional etiology was suspected. The transition to a new diet based on balanced commercial pellets is ongoing in this aquarium.…”

Relationship between the lipidome profile and disease activity in patients with rheumatoid arthritis

“…Lysophosphatidylcholine is known to exert pro-in ammatory effects. It is highly expressed at in ammatory sites [23], and its expression is followed by in ammatory responses to lysophosphatidylcholine in various cells. A stimulation with lysophosphatidylcholine induced in ammatory responses, such as the expression of adhesion molecules and production of COX-2, in vascular endothelial cells [24], chemotaxis, and proin ammatory cytokine production in monocytic cells [25], and evoked T-cell chemotaxis [26].…”

Mechanisms and Treatment of Light-Induced Retinal Degeneration-Associated Inflammation: Insights from Biochemical Profiling of the Aqueous Humor

“…Consistently, in our model, LIRD is associated with prolonged upregulation of lyso-PAF. Furthermore, PAF can be produced from lyso-PAF (by Lyso-PAF:acetyl-coenzyme A acetyltransferase) or from lysophosphatidyl choline (lyso-PC; biosynthesized by phospolipase A2), the concentration of which also increases in AH during ocular inflammation [57]. Given all of these data, it is not surprising that, in our model, LIRD is associated with prolonged growth in AH concentration of prostaglandins, among which PGF 2α remained elevated, even at the seventh day post-exposure.…”